background: dengue is a global arboviral threat to humans; causing 390 million infections per year. the availability of safe and effective tetravalent dengue vaccine is a global requirement to prevent epidemics, morbidity, and mortality associated with it. methods: five experimental groups (6 mice per group) each of 5-week-old balb/c mice were immunized with vaccine and placebo (empty plasmid) ...

An inverse P-Cygni profile of H13CO+ (1-0) in G31.41+0.31 was recently observed, which indicates the presence an infalling gas envelope. Also, outflow tracer, SiO, observed. Here, exclusive radiative transfer modelings have been implemented to generate synthetic spectra some key species (H13 CO+, HCN, NH3, CH3 CN, CH3OH, CH3SH, and CH3NCO) extract physical features infer excitation conditions s...

objective(s): production of a recombinant and immunogenic antigen using dengue virus type-3 envelope protein is a key point in dengue vaccine development and diagnostic researches. the goals of this study were providing a recombinant protein from dengue virus type-3 envelope protein and evaluation of its immunogenicity in mice. materials and methods: multiple amino acid sequences of different i...

background and aims. wound dehiscence after lower third molar surgery extends the postoperative treatment period and may cause long-standing pain. the aim of this study was to compare wound dehiscence after removal of wisdom teeth in the most prevalent mandibular impaction (mesioangular class ib) by two different soft tissue flap designs. materials and methods. partially-erupted mandibular thir...

A block to polyspermy in amphibians is established at fertilization by the conversion of the vitelline envelope to the fertilization envelope. In Xenopus laevis a major ultrastructural change in the envelope at fertilization is the appearance of an electron-dense layer, termed the F layer, between the envelope and the inner-most jelly coat layer, J(1). The F layer is derived, at least in part, ...

Broadly neutralizing Abs to HIV-1 are well described; however, identification of Ags that elicit these Abs has proven difficult. Persistent infection with GB virus type C (GBV-C) is associated with prolonged survival in HIV-1-infected individuals, and among those without HIV-1 viremia, the presence of Ab to GBV-C glycoprotein E2 is also associated with survival. GBV-C E2 protein inhibits HIV-1 ...

It is possible to increase the intelligibility of speech in noise by enhancing the clean speech signal. In this paper we demonstrate the effects of modifying the spectral envelope of synthetic speech according to the environmental noise. To achieve this, we modify Mel cepstral coefficients according to an intelligibility measure that accounts for glimpses of speech in noise: the Glimpse Proport...