نتایج جستجو برای: systemic antibiotic

تعداد نتایج: 254729  

2016
Stephan Ehrhardt Nan Guo Rebecca Hinz Stefanie Schoppen Jürgen May Markus Reiser Maximilian Philipp Schroeder Stefan Schmiedel Martin Keuchel Emil C. Reisinger Andreas Langeheinecke Andreas de Weerth Marcus Schuchmann Tom Schaberg Sandra Ligges Maria Eveslage Ralf M. Hagen Gerd D. Burchard Ansgar W. Lohse Bernhard Ruf Rainer Porschen Guido Trenn Trude Butterfaß-Bahloul Gudrun Wuerthwein Frank Oeder Andreas Runge Esther Klauss Nina Hansen-Rosenblatt Tobias Werner Kornelius Schulze Benno Kreuels Guido Schäfer Peter Hübener Annette Hennigs Claudia Beisel Dorothee Fischer-Brügge Katharina Zimmermann-Fraedrich Claudia Röder Nadine Grigo Armin Riecke Helmut Schreckenbauer Christoph Hemmer Sebastian Klammt Hilte Geerdes-Fenge Silvius Frimmel Jens M. Kittner Johannes W. Rey Joern M. Schattenberg Florian Thieringer Rudolf Schmits Daniel Grandt Philipp Martin Büch Alexander Klebert Marc Andreas Mittag Sybille Lehnen Daniel Tiefengraber Klaus Radecke Iris Hering Wolfgang Zeller Lisa Rundt Lars Brandt Peter Baltes Dani Dajani Niehls Kurniawan Carola Pflüger Nassim Behjat Ulrike Engel Martina Unger

Background.  Antibiotic-associated diarrhea (AAD) and Clostridium difficile-associated diarrhea (CDAD) are common complications of antibiotic use. Data on the efficacy of probiotics to prevent AAD and CDAD are unclear. We aimed to evaluate the efficacy of Saccharomyces boulardii to prevent AAD and CDAD in hospitalized adult patients. Methods.  We conducted a multicenter, phase III, double-maske...

Journal: :European Journal of Clinical Microbiology & Infectious Diseases 2010

Journal: :JAMA 1995
M H Eckman S Greenfield W C Mackey J B Wong S Kaplan L Sullivan K Dukes S G Pauker

OBJECTIVE To examine the cost-effectiveness of approaches to the diagnosis and treatment of patients with type II (non-insulin-dependent) diabetes mellitus (NIDDM) who have foot infections and suspected osteomyelitis. DESIGN Decision and cost-effectiveness analyses were performed using a Markov model. We examined the prevalence of osteomyelitis, the major complications and efficacies of long-...

2007
A. Bignon F. Laurent J. Goldnadel J. Chevalier G. Fantozzi E. Viguier T. Roger G. Boivin D. Hartmann

Despite systemic prophylaxis, infection rates after orthopedic surgery can reach more than 1%. A new HAP/TCP bone substitute loaded with 125 mg of gentamicin was designed for prophylactic use. Its aim was to enhance the efficacy of systemic prophylactic treatments by increasing the local antibiotic concentration. For prophylactic applications, release had to take place within 48 hours not to se...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012
Brad Spellberg Benjamin A Lipsky

The standard recommendation for treating chronic osteomyelitis is 6 weeks of parenteral antibiotic therapy. However, oral antibiotics are available that achieve adequate levels in bone, and there are now more published studies of oral than parenteral antibiotic therapy for patients with chronic osteomyelitis. Oral and parenteral therapies achieve similar cure rates; however, oral therapy avoids...

2014
Michael Meisner

Procalcitonin (PCT) is used as a biomarker for the diagnosis of sepsis, severe sepsis and septic shock. At the same time, PCT has also been used to guide antibiotic therapy. This review outlines the main indications for PCT measurement and points out possible pitfalls. The classic indications for PCT measurement are: (i) confirmation or exclusion of diagnosis of sepsis, severe sepsis, or septic...

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