Introduction: According to some studies, Ramadan fasting causes minimal changes in the levels of thyroid hormones. The present study aimed to evaluate the impact of Ramadan fasting on the levels of thyroid hormones in fasting women with hypothyroidism and levothyroxine intake. Methods: Serum levels of free thyroxine (T4) and thyroid-stimulating hormone (TSH) we...

The present study examined the thyroid function and low T3 state in a group of patients exposed to different concentration of fluoride in drinking water. 139 subjects from severe endemic fluorosis areas and 140 subjects as control group were randomly selected. The functional activity of thyroid gland was measured and the findings indicate that the level of TSH and rT3 was significantly (P<0.001...

BACKGROUND Perchlorate is commonly found in the environment and known to inhibit thyroid function at high doses. Assessing the potential effect of low-level exposure to perchlorate on thyroid function is an area of ongoing research. OBJECTIVES We evaluated the potential relationship between urinary levels of perchlorate and serum levels of thyroid stimulating hormone (TSH) and total thyroxine...

Administration of the anticonvulsant 5,5-diphenylhydantoin sodium (DPH, Dilantin) depresses the level of serum protein-bound iodine (PBI) without inducing clinical hypothyroidism or changing other measures of thyroid function, such as 24-hour thyroidal accumulation of I131, thyroidal clearance of I131, serum cholesterol, and basal metabolic rate (1). Since DPH also induces a fall in the serum P...

Objective The current study was aimed at analyzing sarcoplasmic reticulum Ca2+ ATPase (Serca2) and ryanodine receptor type 2 (Ryr2) gene expression in rats subjected to surgery that induced HF and were subsequently treated with T4 using physiological doses. Materials and methods HF was induced in 18 male Wistar rats by clipping the ascending thoracic aorta to generate aortic stenosis (HFS gro...

To assess the toxicological significance of thyroidal tumor observed slightly in a long-term rat study with diniconazole, (E)-1-(2,4-dichlorophenyl)- 4,4-dimethyl-2-(1,2,4-triazol-1-yl)-1-penten-3-ol, a 3-month subacute feeding study was conducted in male Crj: CD (SD) rats by administering diniconazole in diet at concentrations of 0, 100, 1,000, or 2,000 ppm. Examinations mainly for thyroid fun...

Background: The secretion of thyroxin (T4) as the main hormone of thyroid gland is regulated by androgens. The present study aimed to evaluate the effect of testosterone and finasteride administration and castration on serum levels of T4 and to show the effect of this regulation on total body weight, weight of testis, and the weight of prostate. Methods: Male adult rats (n = 32) were divided in...

Thirty-two weaned male Barbari kids (av. age, 144.65 days; weight, 9.43±0.24 kg), reared under intensive system of feeding, were divided equally into four groups (T1, T2, T3 and T4) to investigate the effect supplementation different levels concentrate mixture on voluntary intake, growth performance, carcass traits quality. All fed with Bengal gram straw ad lib. + green fodder as basal ration s...

The presence of cervical metastasis has substantial negative impact on survival of patients with laryngeal cancer. Bilateral elective selective neck dissection of levels II, III and IV is usually the chosen approach in these patients. However, there is significant morbidity associated with level IV dissection, such as phrenic nerve injury and lymphatic fistula. The objective of the present stud...