Ethylenediaminetetraacetic acid (EDTA)-treated dentin matrix (TDM) is an enriched source of bioactive molecules. Therefore, it was hypothesized that fabrication of autogenous TDM on root dentinal walls of necrotic immature permanent teeth may allow more predictable outcome of revascularization treatments. Two young patients with permanent nonvital immature teeth were chosen for revascularizatio...

BACKGROUND The existing literature suggests that the surgical mortality (SM) observed with nephrectomy for localised disease varies from 0.6% to 3.6%. OBJECTIVE To examine age- and stage-specific 30-d mortality (TDM) rates after partial or radical nephrectomy. DESIGN, SETTING, AND PARTICIPANTS We relied on 24535 assessable patients from the National Cancer Institute (NCI) Surveillance, Epid...

This paper studies the routing and wavelength assignment problem for a circuit-switched time division multiplexed (TDM) wavelength-routed (WR) optical WDM network. In a conventional wavelength routed network, an entire wavelength is assigned to a given session (or circuit). This can lead to lower channel utilization when the individual sessions do not need the entire channel bandwidth. This pap...

Interest in therapeutic drug monitoring (TDM) as an adjunct in the management of HIV infection has increased in recent years. The protease inhibitors (PIs) have stimulated the most interest in TDM as they have considerable interand intra-individual variability in plasma levels and marked potential for drug interactions that may lead to reduced or elevated PI plasma concentrations. There may als...

BACKGROUND Standard applicators for cervical cancer Brachytherapy (BT) do not always achieve acceptable balance between target volume and normal tissue irradiation. We aimed to develop an innovative method of Target-volume Density Mapping (TDM) for modelling of novel applicator prototypes with optimal coverage characteristics. Patients and methods. Development of Contour-Analysis Tool 2 (CAT-2)...

Triamidefon is a triazole derivative, which have both fungicidal and plant growth regulator (PGR) properties, and also protect plants from several types of abiotic stresses. The influential mechanism of Triamidefon on plants is not much studied. In this study effect of this compound on the drought stressed in tomato plants was investigated. The plants were subjected to 5 day interval drought st...

Abstract Technical Debt Management (TDM) includes activities such as identifying, measuring, and prioritizing technical debt. It is mainly performed to proactively mitigate the risk of losing maintainability evolvability software product which results in reducing team velocity. Despite importance TDM, its adoption companies remain limited. Software are witnessing high market demand competition ...

Several anticancer drugs display characteristics that make them suitable candidates for therapeutic drug monitoring (TDM), including substantial pharmacokinetic variability and a narrow therapeutic index. However, concentration-effect relationships (pharmacodynamics) of most antineoplastic agents have not been well defined, thus limiting the widespread clinical application of TDM for cancer che...

Declarative approaches to process modeling promise a high degree of flexibility. However, current declarative state-of-the-art modeling notations are, while sound on a technical level, hard to understand. To cater for this problem, in particular to improve the understandability of declarative process models as well as the communication between domain experts and model builders, Test Driven Mode...

The study "Alexander" on bacterial resistance to antibiotics conducted in Poland revealed high sensitivity of bacterial strains to simple and cheap antibiotics. In Poland pharmacoeconomic studies on the safety, effectiveness and costs of treatment are rare. Development of therapeutic standards in bacterial infections on the basis of pharmacoeconomic analyses and clinical studies determining eff...