نتایج جستجو برای: tdx filter
تعداد نتایج: 123485 فیلتر نتایج به سال:
WE HAVE evaluated the usefulness of a fluorescent polarization immunoassay (FPIA) utilizing the Abbott TD.· technology for the routine measurements of cyclosporine in whole blood or plasma. This procedure was compared with the Sandoz radioimmunoassay. The evaluation was undertaken in an effort to decrease the radioactive hazard, and contain the reagent and supply costs, as well as to reduce the...
Although cocaine is typically the second-most identified drug of abuse in drug-testing programs, there is surprisingly little quantitative information on excretion patterns following different routes of administration. This report details the urinary excretion and terminal elimination kinetics for cocaine and eight metabolites [benzoylecgonine (BZE), ecgonine methylester (EME), norcocaine (NCOC...
The objective of this study was to evaluate the analytical performance of the Abbott ARCHITECT Cyclosporine (CsA) immunoassay in 7 clinical laboratories in comparison to liquid chromatography/tandem mass spectrometry (LC/MS/MS), Abbott TDx, Cobas Integra 800, and the Dade Dimension Xpand immunoassay. The ARCHITECT assay uses a whole blood specimen, a pretreatment step with organic reagents to p...
an air filter is a significant element of any mechanical ventilation system. however, the importance and performance evaluation of air filters have not been well publicized and related scientific reports are scarce. in this study, a transportable, off-line, air filter-testing unit (the unit) was designed and utilized to simulate the filter housing of a mechanical ventilation system. the unit wa...
Thymidylate synthase (TS), a critical enzyme in the de novo synthesis of thymidylate, is an important target for fluoropyrimidines and folate-based TS inhibitors. In a panel of 13 nonselected human colon cancer cell lines, we evaluated the role of TS levels in sensitivity to 5-fluorouracil (5FU) and four folate-based TS inhibitors that have been introduced recently into the clinic: ZD1694 (Tomu...
A new procedure for measuring cyclosporine in plasma has been introduced by Abbott Laboratories, involving their TDx instrumentation and fluorescence polarization immunoassay. Radioimmunoassay (RIA) and high-performance liquid chromatography are currently the conventional methods for measuring cyclosporine in plasma and whole blood. In an effort to find a method that will decrease the radioacti...
A fluorescence polarization immunoassay for barbiturates on the Abbott AxSYM analyzer is described. The assay displayed dilution linearity up to 1200 ng/mL; coefficients of variation varied from 5.96 to 8.61%; recovery varied from 94.9 to 105.3%; and sensitivity was less than 40 ng/mL. Good correlation between the standard six- and factory two-point calibration methods was observed. The Immunoa...
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