Pseudomonas pseudoalcaligenes KF707 is naturally resistant to the toxic metalloid tellurite, but the mechanisms of resistance are not known. In this study we report the isolation of a KF707 mutant (T5) with hyperresistance to tellurite. In order to characterize the bacterial response and the pathways leading to tolerance, we utilized Phenotype MicroArray technology (Biolog) and a metabolomic te...

A series of glass samples the tungsten–tellurite system TeO2-WO3-Bi2O3-(4-x) La2O3-xEr2O3, x = 0; 0.4; 0.5; 0.7; 1.2; 2; 4 mol%, CEr 0 - 15 × 1020 cm?3 were synthesized from high-purity oxides in an oxygen flow inside a specialized sealed reactor. In all series, extremely low content hydroxyl groups was achieved (~n 1016 cm?3, more than orders magnitude lower concentration erbium ions), which g...

We report on a self-organized process initiated potassium-tungsten-tellurite glass surface under repetitive femtosecond laser irradiation in regime where cumulative effects lead to localized melting. Specifically, we show that periodic patterns consisting of parallel nanoplanes perpendicular the polarization are forming and extending beyond zone direct exposure. Examination modified regions rev...

Mercury salts and tellurite are among the most toxic compounds for microorganisms on Earth. Bacterial mercury resistance is established mainly via mercury reduction by the mer operon system. However, specific mechanisms underlying tellurite resistance are unknown to date. To identify new mechanisms for tellurite detoxification we demonstrate that mercury resistance mechanisms can trigger cross-...

The respiratory chain of Pseudomonas pseudoalcaligenes KF707 in membranes isolated from cells grown in the presence or absence of the toxic oxyanion tellurite (TeO3(2-)) was examined. Aerobic growth in the absence of tellurite shows an NADH-dependent respiration which is 80% catalysed by the cytochrome (cyt) bc1-containing pathway leading to two terminal membrane-bound cyt c oxidases inhibited ...

During an attempt to test current, and develop new, histochemical methods applicable to electron microscopy, early success was obtained with a method for demonstrating the activity of dehydrogenase systems. This method depends on the fact that potassium tellurite (K2TeOa) is reduced (hydrogenated) by living tissues to a product of high electron-scattering power. More specifically, this reagent ...

Reactive oxygen species damage intracellular targets and are implicated in cancer, genetic disease, mutagenesis, and aging. Catalases are among the key enzymatic defenses against one of the most physiologically abundant reactive oxygen species, hydrogen peroxide. The well-studied, heme-dependent catalases accelerate the rate of the dismutation of peroxide to molecular oxygen and water with near...