BACKGROUND Pain affects millions of people worldwide, opioid analgesics have been used for chronic painful conditions. Due to their adverse effects, safer alternatives would be beneficial. Terminalia chebula, with proven analgesic action has been evaluated in the hot air pain model for its analgesic activity. AIM To evaluate analgesic activity and safety of single oral dose of Terminalia cheb...

Objective: The aim of the study was to explore the protective activity of Terminalia chebula fruit extract on cardiotoxicity in streptozotocin (STZ) induced diabetic rats. Methods: The animals were divided into eight groups of five each and were fed with high fat diet (HFD) except sham control, diabetic control and isoproterenol control. Diabetes was induced by administering single intraperiton...

Thirty-seven plant organs, traditionally used as drugs, collected in Pakistan, were extracted with 70% acetone and analyzed for their total phenolics concentration and antioxidant potential. Seven extracts showed more than 85% inhibition of lipid peroxidation in vitro as compared with blank. Butylated hydroxytoluene (BHT) (IC50 = 233.6 microg/l +/- 28.3) was the strongest antioxidant in our tes...

Objective: To study the anti-arthritic activity of Acetone Extract of fruits of Terminalia chebula (TCE) in wistar rats in an experimental model of rheumatoid arthritis. Materials and methods: After necessary approval from Institutional Animal Ethics Committee (IAEC), 28 wistar albino rats of either sex (150-200gm) were randomly divide into 7 groups. Arthritis was induced in all animals by intr...

Terminalia belerica (behada) fruit has been evaluated as a promising agent against E. histolytica and a variety of bacteria associated with dysentery and diarrhoea. These in vitro studies were extended further for evaluating clinical efficacy among patients of acute and chronic cases of diarrhoea and dysentery. The Studies were carried out on 25 patients by five medical practitioners practicing...

The male, female and puparium are described for Sarcofahrtiopsis cupendipe sp. nov., whose larvae live in the roosts of disk-winged bats (Thyroptera species). Sarcofahrtiopsis cupendipe and S. thyropteronthos Pape, Dechmann & Vonhof are both associated with the faeces of the disk-winged bat and are the only species of Sarcofahrtiopsis with wing vein R1 fully setose dorsally and a sho...

the present study has been designed to find out the protective effect of aqueus extract of terminalia arjuna against dehydration induced oxidative stress and uremia, protection by plant extract in male wister strain albino rats, and therefore to find out the scientific basis of local use of terminalia arjuna bark extract by village ayurved doctors to protect the progressive kidney disorder (ren...

The ethanol extract of the root bark of Terminalia sericea yielded an unreported stilbene glycoside, 3'5'-dihydroxy-4-(2-hydroxy-ethoxy) resveratrol-3-O-beta-rutinoside (1) together with known compounds resveratrol-3-beta-rutinoside glycoside (2), 3',4,5'-Trihydroxystilbene (resveratrol) (3), triterpenoic acid arjungenin and a mixture of beta-sitosterol and stigmasterol. Structure determination...

The present study was designed to investigate the cardio protective role of chronic oral administration of alcoholic extract of Terminalia arjuna in in-vivo ischemic reperfusion injury and the induction of HSP72. Rabbits, divided into three groups, and were administered with the alcoholic extract of the bark powder of Terminalia arjuna (TAAE) by oral gavage [6.75mg/kg: (T1) and 9.75mg/kg: (T2),...

PURPOSE Kidney stone is one of the most prevalent diseases worldwide. Calcium oxalate (CaOx) has been shown to be the main component of the majority of stones formed in the urinary system of the patients with urolithiasis. The present study evaluates the antilithiatic properties of Terminalia chebula commonly called as ″harad ″ which is often used in ayurveda to treat various urinary diseases i...