نتایج جستجو برای: tetanus toxin
تعداد نتایج: 58433 فیلتر نتایج به سال:
Tetanus is caused by the toxin secreted by Clostridium tetani. Due to the rapid infection with this bacterium, it is so important to investigate the tetanus immunity of people. Therefore, electrochemical biosensors, as one of the most effective tools in this regard, have demanded characteristics such as being fast, simple, cost-effective and portable. However, their detection sensitivity is not...
It has previously been reported' that during the production of tetanus toxin in the Mueller Medium, the medium becomes dark and turbid in about 24 hours, followed by clearing in four or five days. When clearing occurs, maximum toxin production or release is obtained as measured by Lf units. The simultaneous occurrence of clearing and presence of maximum Lf value has been attributed to "autolysi...
For the first time, bacterial spores have been evaluated as vaccine vehicles. Bacillus subtilis spores displaying the tetanus toxin fragment C (TTFC) antigen were used for oral and intranasal immunization and were shown to generate mucosal and systemic responses in a murine model. TTFC-specific immunoglobulin G titers in serum (determined by enzyme-linked immunosorbent assay) reached significan...
Postimmunization human B lymphocytes and mouse myeloma cells were fused to produce interspecies hybridomas secreting human antibody of predefined specificity with an initial frequency comparable to intraspecies fusion. After 13 mo in culture, one clone continued to secrete high titers of human IgG antitetanus toxin antibody. This antibody binds to the B fragment of tetanus toxin and protects mi...
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