Indirect evidence suggests that the thalamus contributes to abnormal movements occurring in patients with dystonia (dystonia patients). The present study tested the hypothesis that thalamic activity contributes to the dystonic movements that occur in such patients. During these movements, spectral analysis of electromyographic (EMG) signals in flexor and extensor muscles of the wrist and elbow ...

Neurology 2012;78:1708–1709 Ever since Gloor et al.1 demonstrated that thalamocortical interactions were responsible for generalized seizures, alterations of thalamic function have been investigated in the pathophysiology of epilepsy. Today, the thalamus (in its regulatory, synchronizing actions with the cortex) has been assigned diverse roles. To name just two: 1) in potentiating seizure occur...

as one of the most promising distributed generation (dg) sources, wind power technology has been widely developed in recent years. doubly fed induction generator (dfig) is currently employed as one of the most common topologies for wind turbine generators (wtgs). this generator operates as a synchronous/asynchronous hybrid generators. therefore, it is necessary to power engineers find understan...

BACKGROUND Although the mechanisms of short- and long-term potentiation of nociceptive-evoked responses are well known in the spinal cord, including central sensitization, there has been a growing body of information on such events in the cerebral cortex. In view of the importance of anterior cingulate cortex (ACC) in chronic pain conditions, this review considers neuronal plasticities in the t...

We studied the effectiveness of electrical stimulation treatment in 10 cases with central (thalamic) pain. Pain was caused by thalamic hemorrhage in 6 cases. There was one case each of putamino– thalamic, putaminal, pontine hemorrhage and thalamic infarct. We were able to achieve sufficient and long–term pain control by epidural spinal cord stimulation in all 4 cases in which pain was localized...

Deep brain stimulation (DBS) is one of the most effective therapies for movement and other disorders. The DBS neurosurgical procedure involves the implantation of a DBS device and a battery-operated neurotransmitter, which delivers electrical impulses to treatment targets through implanted electrodes. The DBS modulates the neuronal activities in the brain nucleus for improving physiological res...

Visual responses in the cortex are generated by the interactions of feedforward thalamic inputs with local inhibitory and excitatory circuitry, but the exact roles of different cell types in establishing response selectivity are unclear. Two papers in this issue of Neuron (Kerlin et al. and Runyan et al.) combine two-photon imaging with guided electrical recordings to measure orientation tuning...

In the preceding papers of this series, we have analyzed the cellular patterns and synchronization of neocortical seizures occurring spontaneously or induced by electrical stimulation or cortical infusion of bicuculline under a variety of experimental conditions, including natural states of vigilance in behaving animals and acute preparations under different anesthetics. The seizures consisted ...