Abstract Background Stroke in children easily causes long-term dysfunction. Whether the prognoses of motor and anxiety disorders are related to affected stroke area has not been reported. Methods One hundred nine cases with ischaemic were reviewed divided into three groups: lenticular nucleus lesions only (lenticular group), caudate head (caudate thalamus (thalamus group). Overall prognosis was...

Genes of the Major Histocompatibility Complex (MHC) have recently been shown to have neuronal functions in the thalamus and hippocampus. Common genetic variants in the Human Leukocyte Antigens (HLA) region, human homologue of the MHC locus, are associated with small effects on susceptibility to schizophrenia, while volumetric changes of the thalamus and hippocampus have also been linked to schi...

Although neurons within intact nervous systems can be classified as 'sensory' or 'motor,' it is not known whether there is any general distinction between sensory and motor neurons at the cellular or molecular levels. Here, we extend and test a theory according to which activation of certain subtypes of voltage-gated ion channel (VGC) generate patterns of spikes in neurons of motor systems, whe...

The thalamus is a critical component of the frontal cortical-basal ganglia-thalamic circuits that mediate motivation and emotional drive, planning and cognition for the development and expression of goal-directed behaviors. Each functional region of the frontal cortex is connected with specific areas of each basal ganglia (BG) structure and of the thalamus. In addition, the thalamus sends a mas...

Case reports of two patients with cerebellar ataxia and proprioceptive sensory loss are presented. MRI of the brain revealed lesions of the ventroposterior part of the thalamus. These patients illustrate clinically the anatomical independence of cerebellar and sensory pathways in the thalamus. We suggest that the ataxic deficit is caused by interruption of cerebellar outflow pathways in the tha...

OBJECTIVES The purpose of this study was to assess N-acetyl aspartate changes in the thalamus in patients with osteoarthritis of the hip using proton magnetic resonance spectroscopy. METHODS Nine patients with osteoarthritis of the hip (symptomatic group, nine women; mean age 61.4 years (48 to 78)) and nine healthy volunteers (control group, six men, three women; mean age 30.0 years (26 to 38...

1166_1664 Ad (297X115)NEW FA.indd 3 2013/08/19 2:50 PM Academy of Science of South Africa survey: Responsibility in the life sciences To the Editor: The Academy of Science of South Africa (ASSAf) would like to invite all practising life scientists in research and diagnostic facilities to take part in a nationwide survey. The survey is based on a questionnaire designed by the World Health Organi...

Objective: We investigated changes in cortico–subcortical spatiotemporal dynamics to explore the treatment mechanisms of transcranial alternating current stimulation (tACS) patients with Parkinson’s disease (PD). Methods: Resting-state functional magnetic resonance imaging (rs-fMRI) data were collected from 20 PD and normal controls (NC). Each patient received successive multidisciplinary inten...

Case presentation: A two year-old previously-healthy male was admitted at the emergency room due to severe acute respiratory syndrome. Initial evaluation detected right pneumonia and ipsilateral pleural effusion. nasopharyngeal SARS-COV-2 RT-PCR test positive. He for intravenous treatment and, after 7 days, presented a decreased level of consciousness left hemiparesis. CT scan normal spinal flu...

Background and objective Cerebral autosomal dominant arteriopathy with subcortical infarcts leukoencephalopathy (CADASIL) is an inherited cerebral microvascular disease characterized by the development of vascular dementia lacunar infarctions. This study aimed to identify genetic clinical features CADASIL in Japan. Methods We conducted analysis on a case series patients clinically diagnosed CAD...