A case of rumen acidosis in non-lactating cattle is reported. This was due to the fact that stale bread was fed ad lib, rather than concentrates. Of seventy animals, fourteen died or were slaughtered. The meat was declared unfit for human consumption in every case.

BACKGROUND Impaired insulin signalling is increasingly thought to contribute to Alzheimer's disease (AD). The ε4 isoform of the APOE gene is the greatest genetic risk factor for sporadic, late onset AD, and is also associated with risk for type 2 diabetes mellitus (T2DM). Neuropathological studies reported the highest number of AD lesions in brain tissue of ε4 diabetic patients. However other s...

Rats, either fed a solid standard chow ad libitum or starved for 24 h prior to the beginning of the experiments, were kept in a normal light-dark cycle of 12 h. At certain times over a total period of 24 h, three animals of each group were killed, their pancreata were excised and the protein synthetic capacity was determined, measuring both the amount of cellular RNA and the percentage of ribos...

Encephalartos hildebrandtii flour was prepared as described in the previous paper (Mugera and Nderito, 1968). The basal diet consisted of commercially available chicken mash, on which excellent growth of the control animals was obtained. The Encephalartos hildebrandtii flour was thoroughly mixed with the basal diet to give a 5 per cent concentration and fed to rats ad libitum. These were male a...

Abnormal phosphorylation and aggregation of tau is a key hallmark of Alzheimer's disease (AD). AD is a multifactorial neurodegenerative disorder for which Diabetes Mellitus (DM) is a risk factor. In animal models for DM, the phosphorylation and aggregation of tau is induced or exacerbated, however the underlying mechanism is unknown. In addition to the metabolic dysfunction, DM is characterized...

triazine derivatives are small synthetic peptides with no apparent toxicity and high target specificity in central nervous system. hippocampal tissue is the most vulnerable area in the alzheimer’s disease (ad). the aim of this study was to investigate the neuroprotective effect of triazine in ad induced by intra-cerebro-ventricular (i.c.v.) administration of streptozotocine (stz). male wistar, ...

Cattle fed grass silage diets have been reported to have high carcass fat:protein ratios. The effect of grass silage and dried grass diets, fed at different levels of intake to ensure a range of equivalent metabolisable energy intakes (MEI) from 1 .1 x metabolisable energy requirement for maintenance to ad libitum, on fat and protein metabolism in twenty-four Hereford x Friesian steers was inve...

Metabolically intact NMRI mice and genetically obese NZO mice were fed ad lib. either a high-carbohydrate diet (standard) or a high-fat diet for a period of about 11 (NMRI mice) or 38 (NZO mice) wk. In both strains of mice, body weight increased more in the groups fed the high-fat diet. However, caloric intake by NMRI mice fed the high-fat diet was less than that of the controls. In NMRI mice f...

We compared fat distribution and lipoprotein lipase (LPL) activity in steers differing in adaptability to the subtropics. Steers were fed a grain diet (3.13 Mcal ME/kg DM) at limited (150 kcal ME x kg[-.75] x d[-1]; .23 kg ADG) or ad libitum levels for 140 d, then slaughtered. Sixteen British- (8 Angus, 8 Hereford; S), 16 Boran- (R), 16 Brahman- (B), and 16 Tuli- (T) cross steers from MARC III ...

Ascorbic acid (vitamin C) supplementation has been documented as a useful tool to improve the performance of laying birds reared under harsh environmental conditions. However, there is limited information on the use of ascorbic acid as a means of ameliorating the stressful conditions imposed by feed restriction. To this effect a 3 × 2 factorial experiment was carried out to evaluate the effect ...