Daily energy restriction more effectively reduces body fat content than alternate-day fasting, with no evidence of fasting-specific health benefits.

Infants with congenital hyperinsulinism owing to inactivating mutations in the K(ATP) channel (K(ATP)HI) who are unresponsive to medical therapy will require pancreatectomy to control the hypoglycemia. In preclinical studies, we showed that the GLP-1 receptor antagonist exendin-(9-39) suppresses insulin secretion and corrects fasting hypoglycemia in SUR-1(-/-) mice. The aim of this study was to...

Pinitol (3-O-methyl-D-chiro-inositol) was identified in putative insulin mediator fractions that have hypoglycemic activity, and appears to mimic the act effects of insulin by acting downstream in the insulin signaling pathway. We evaluated the effect of pinitol therapy in type 2 diabetic patients who were poorly controlled with hypoglycemic drugs, such as sulfonylurea, metformin and/or insulin...

INTRODUCTION Insulin sensitizing drugs such as pioglitazone are not uniformly treatment effective among individual type 2 diabetic patients. Here, the relationship of pioglitazone efficacy to single nucleotide polymorphisms (SNP) of the adiponectin gene, a critical gene directly regulated by the drug, was examined in a cohort of Chinese Han type 2 diabetic patients. METHODS Eighty type 2 diab...

the aim of the study was to investigate the effect resistance trainingon pulmonary function of obese women with type ii diabetes. twenty four  patients with diabetes type ii, aged 40-55 years, mean body mass index (bmi) 30.16 ± 3.26 kg.m² and fasting blood glucose greater than 126 mg.dl were selected purposefully. after anthropometric measurements and indices of lung, subjects were randomly div...

The 15th medical congress of the Medical Association for Fasting and Nutrition (German: Ärztegesellschaft Heilfasten und Ernährung, ÄGHE) took place on June 29–30, 2013 in Überlingen, Germany. This congress was organized in association with the Maria Buchinger Foundation and the Buchinger Wilhelmi Clinics in the course of their anniversary years; 60 years in Überlingen, Germany, and 40 years in...

A link between metabolism and brain function is clear. Since ancient times, epileptic seizures were noted as treatable with fasting, and historical observations of the therapeutic benefits of fasting on epilepsy were confirmed nearly 100 years ago. Shortly thereafter a high fat, low-carbohydrate ketogenic diet (KD) debuted as a therapy to reduce seizures. This strict regimen could mimic the met...

Since the first ADA working group report on the recommendations for management of diabetes during Ramadan in 2005 and our update in 2010, we received many inquiries asking for regular updates on information regarding education, nutritional habits and new oral and injectable agents that may be useful for the management of patients with diabetes during Ramadan. Patients can be stratified into the...

fasting and diabetes has been on my radar from a local perspective for years. as a dietitian many of my patients chose to fast with the goal to promote better health. most recently, my perspective on fasting became global as working with the managing diabetes during ramadan initiatives.in april 2016, international diabetes federation (idf) and the diabetes and ramadan (dar) international allian...

Gender is a major determinant of the outcomes of many health interventions. This study documents the order of significant improvements in metabolic parameters of patients with type 2 diabetes mellitus (T2DM) having metabolic syndrome within 12 weeks of physical exercise programmes. Twenty-nine patients, mean age 49.6 ± 3.7 years, presenting with high fasting plasma glucose, high triglycerides, ...