نتایج جستجو برای: thiazolidin 4 one

تعداد نتایج: 3010807  

Journal: :Acta Crystallographica Section C Crystal Structure Communications 2002

2008
A. D. Taranalli A. R. Bhat S. Srinivas E. Saravanan

The thiazolidin-4-one derivatives and the corresponding spiro compounds were synthesized from sulphanilamide and were evaluated for anti-inflammatory and analgesic activity in acute and sub acute models. Compounds were also evaluated for antipyretic and cyclooxygenase enzyme inhibitory activity. All the compounds showed significant antiinflammatory, analgesic and antipyretic activity at 100 mg/...

Journal: :the iranian journal of pharmaceutical research 0
barbaros eroglu hacettepe university, faculty of pharmacy, department of pharmaceutical chemistry ozadali sari keriman hacettepe university, faculty of pharmacy, department of pharmaceutical chemistry oya unsal tan hacettepe university, faculty of pharmacy, department of pharmaceutical chemistry sriram dharmarajan medicinal chemistry & antimycobacterial research laboratory, pharmacy group, birla institute of technology & science perumal yogeeswari medicinal chemistry & antimycobacterial research laboratory, pharmacy group, birla institute of technology & science ayla balkan department of pharmaceutical chemistry, faculty of pharmacy, hacettepe university

to develop novel antimycobacterial agents, a new series of thiazolidinone-azole hybrids 4a-b, 5a-b and 6-13 were designed and synthesized. thiazolidin-4-ones (4a-b and 5a-b) were obtained by the reaction of schiff bases and hydrazones (2a-b and 3a-b) with mercaptoacetic acid. 5-benzylidene derivatives (6-13) were gained by treatment of 5a-b with appropriate benzaldehydes according to knoevenage...

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