The purpose of this study was to clarify the influence of skin thickness on the in vitro permeabilities of 3 model drugs with different physicochemical properties (nicorandil (NR), isosorbide dinitrate (ISDN) and flurbiprofen (FP)) through Sprague-Dawley rat (rat) or Yucatan micropig (YMP) skin. Intact, dermis-split, stratum corneum-stripped or stratum corneum-stripped and dermis-split rat or Y...

Grapevine is a world-wide cultivated economically relevant crop. The process of berry ripening is non-climacteric and does not rely on the sole ethylene signal. Abscisic acid (ABA) is recognized as an important hormone of ripening inception and color development in ripening berries. In order to elucidate the effect of this signal at the molecular level, pre-véraison berries were treated ex vivo...

This work aimed to elucidate the primary factors which affect skin temperature. A simple thermophysical model of skin, accounts for radiative, convective, and evaporative heat losses, has been developed address it. The is based on skin’s morphology consists passive (nonviable tissue) active (viable layers. bioheat equation was solved these layers using realistic assumptions. It found that other...

Objective. Skin thickness can be a major factor affecting rhinoplasty outcomes. However, few studies have examined the impact of nasal skin thickness on rhinoplasty aesthetic results. The aim of this study is to determine the effect of nasal skin thickness on the tip surgery outcome objectively. Study Design. Case series with chart review. Setting. Academic tertiary care medical center. Subject...

Grapevine fruit development is a dynamic process that can be divided into three stages: formation (I), lag (II), and ripening (III), in which physiological and biochemical changes occur, leading to cell differentiation and accumulation of different solutes. These stages can be positively or negatively affected by multiple environmental factors. During the last decade, efforts have been made to ...

Climatic conditions and soil type have significant influence on grape ripening and wine quality. The reported study was conducted in two "Cabernet Sauvignon (Vitis vinifera L.V)" vineyards located in Xinjiang, a semiarid wine-producing region of China during two vintages (2011 and 2012). The results indicate that soil and climate affected berry growth and anthocyanin profiles. These two localit...

The influence of age, sex, body mass index (BM!) and skin fold thickness at triceps and subscapular regions on blood pressure was investigated among Manzai Mali, an agricultural tribe from Andhra Pradesh. Relatively higher levels of blood pressure are observed in this . transitional tribe compared to the neighbouring traditional tribes which may be attributed to the acculturization process. Man...