Previous studies have demonstrated that elevated plasma leptin concentrations are associated with essential hypertension. It has also recently been shown that leptin plays a promoting role in angiogenesis, and the vascular endothelium expresses the long form of leptin receptor. Those data led us to hypothesize that leptin might contribute to end-organ damage in hypertension. Thus, in the presen...

OBJECTIVE To investigate the economic impact of introducing targeted screening and laser photocoagulation treatment for sight-threatening diabetic retinopathy and macular edema in a setting with no previous screening or laser treatment for diabetic retinopathy in sub-Saharan Africa. MATERIALS AND METHODS A cohort Markov model was built to compare combined targeted screening and laser treatmen...

diabetic retinopathy is the leading cause of blindness in the world. strict control of blood sugar, blood pressure, laser therapy, pharmacotherapy and vitrectomy are of among common diabetic retinopathy treatments. further studies to investigate the effect of protein kinase c inhibitors, angiotensin converting enzyme inhibitors, growth hormone and other proposed treatments for diabetic retinopa...

purpose : the objective of this study was to investigate the causes, the clinical presentation, and treatment modalities in patients with valsalva premacular hemorrhage. methods : this case series study included 21 eyes of 21 patients referred to retina clinic of farabi eye hospital and two private eye clinics during 2001-2006 with sudden loss of vision and clinical diagnosis of premacular hemo...

AIMS Visual outcome of 66 eyes in 37 patients who had undergone treatment with either cryotherapy or diode laser for threshold retinopathy of prematurity was assessed. METHODS 17 patients, representing 30 eyes treated with cryotherapy, were examined at between 56 and 98 months corrected age (median 68 months). 20 patients representing 36 eyes treated with diode laser, were examined at between...

purpose : to report a case of purtscher retinopathy associated with valsalva retinopathy after car accident methods : a 54-year-old man presented with a sudden visual loss in his left eye after car accident. fundus examination of the left eye showed cotton-wool spots and retinal hemorrhages in the posterior pole associated with subhyaloid hemorrhage in macula. results : fundus examination showe...