نتایج جستجو برای: thrombopoietin

تعداد نتایج: 1701  

2018
Yasuyuki Arai Tomoyasu Jo Hiroyuki Matsui Tadakazu Kondo Akifumi Takaori-Kondo

Corticosteroids such as prednisolone and dexamethasone have been established as up-front therapy for the treatment of newly diagnosed immune thrombocytopenia. Recent studies have indicated that other treatments such as rituximab or thrombopoietin receptor agonist can also be effective choices. We performed a systematic review and network meta-analysis to establish a clinically meaningful hierar...

Journal: :Blood 1995
T P McDonald P S Sullivan K Kaushansky

2017
Lina Thorén Martin Thorén

Journal: :The New England journal of medicine 2012
Rebecca L Stone Alpa M Nick Iain A McNeish Frances Balkwill Hee Dong Han Justin Bottsford-Miller Rajesha Rupairmoole Guillermo N Armaiz-Pena Chad V Pecot Jermaine Coward Michael T Deavers Hernan G Vasquez Diana Urbauer Charles N Landen Wei Hu Hannah Gershenson Koji Matsuo Mian M K Shahzad Erin R King Ibrahim Tekedereli Bulent Ozpolat Edward H Ahn Virginia K Bond Rui Wang Angela F Drew Francisca Gushiken Donald Lamkin Katherine Collins Koen DeGeest Susan K Lutgendorf Wah Chiu Gabriel Lopez-Berestein Vahid Afshar-Kharghan Anil K Sood

BACKGROUND The mechanisms of paraneoplastic thrombocytosis in ovarian cancer and the role that platelets play in abetting cancer growth are unclear. METHODS We analyzed clinical data on 619 patients with epithelial ovarian cancer to test associations between platelet counts and disease outcome. Human samples and mouse models of epithelial ovarian cancer were used to explore the underlying mec...

Journal: :Journal of Cell Communication and Signaling 2018

Journal: :British Journal of Haematology 1998

Journal: :Blood 2015
Hai Zhou Miao Xu Ping Qin Hai-yan Zhang Cheng-lu Yuan Hong-guo Zhao Zhong-guang Cui Yue-sheng Meng Lei Wang Fang Zhou Xin Wang Da-qi Li Ke-hong Bi Chuan-sheng Zhu Cheng-shan Guo Xiao-xia Chu Qing-chao Wu Xin-guang Liu Xiao-yuan Dong Jie Li Jun Peng Ming Hou

This study aimed to compare the efficacy and safety of rituximab (RTX) plus recombinant human thrombopoietin (rhTPO) with RTX alone in patients with immune thrombocytopenia (ITP) who had failed to respond to corticosteroids or relapsed. Recruited patients were randomized at a ratio of 2:1 into 2 groups: the combination group (RTX + rhTPO, n = 77) and the monotherapy group (RTX, n = 38). Overall...

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