Background: Due to the lack of information about the role of 4G/5G polymorphism of PAI-1 Gene in susceptibility to thyroid tumors, this study was performed to evaluate the potential effects of this polymorphism on clinicopathologic features of thyroid tumors in Iranian Azeri Turkish patients. Methods:In this case-control study, 90 patients with thyroid tumors ...

Background: This investigation systematically evaluated the selenium levels and effects of supplementation in patients with autoimmune thyroid disease (AITD).

objective: diabetes mellitus and thyroid disease are the two common endocrinopathies seen in adult population. studies to evaluate thyroid disorders in patients with type 2 diabetes are lacking. the aim of this study was to compare prevalence of thyroid dysfunction and autoim-munity in type 2 diabetic patients with age and sex matched non-diabetic control group. material and methods: among pati...

Objective(s): The aim of this study was to explore the accuracy of thyroid to background uptake ratio (UR) in the evaluation of 99mTc-pertechnetate thyroid uptake (TcTU) and establishment of an improved algorithm. Methods: This study was conducted on the thyroid images of 322 patients with thyroid diseases and 67 controls. For the purpos...

Patients with IgG4-related disease (IgG4-RD) are diagnosed in Japan by comprehensive or organ-specific diagnostic criteria. To date, criteria have been established for several organs, but not the thyroid. We attempted to establish thyroid (IgG4-RTD) based on IgG4-RD research The Research Program Intractable Diseases from Ministry of Health, Labour and Welfare Japan. These publicly reported memb...

Clinical evidence of a thyroid disorder was present in 10 out of 40 patients with Addison's disease. Though the remaining 30 patients had no clinical evidence of thyroid disease, six (out of 15 tested) had thyroid microsomal antibodies and a considerably impaired response to thyrotrophin. These changes are interpreted as very early indications of developing thyroid failure. When circulating mic...

Autoimmune thyroid disorders are the commonest form of thyroid disease. The presence of autoantibodies against thyroid antigens mainly thyroid peroxidase (anti-TPO) and thyroglobulin (anti-Tg) are the hallmarks for autoimmune thyroid disease. Thyroid disorders and diabetes mutually influence each other but the role of type 2 diabetes in the development of autoimmune thyroid disease is not well ...

BACKGROUND Diabetes mellitus and thyroid diseases frequently coexist. In order to evaluate how thyroid disorders interfere with glycemic control, we analysed insulin-treated type 2 diabetes patients with thyroid disease. METHODS Diabetes patients (n = 1.957) were retrospectively investigated. We focused on type 2 diabetes patients who had been admitted for insulin-treatment and diagnosed thyr...

A well defined cohort of coeliac patients was studied prospectively to assess the prevalence of coexisting thyroid disease and positive thyroid autoantibodies. Comparison with epidemiological data on the prevalence of coeliac disease in a neighbouring area suggested that few adult coeliac patients had been missed. Overall, 14% of the coeliac patients had thyroid disease: 10.3% were hypothyroid ...