Iodine is enriched and stored in the thyroid gland. Due to several factors, the size of the thyroid iodine pool varies both between individuals and within individuals over time. Excess iodine as well as iodine deficiency may promote thyroid cancer. Therefore, knowledge of iodine content and distribution within thyroid cancer tissue is of interest. X-ray fluorescence analysis (XRF) and secondary...

Primary cultures of rat thyroid cells were made in medium supplemented with 0.1--0.5% calf serum and containing six hormones or growth factors: insulin, thyrotropin, transferrin, hydrocortisone, somatostatin, and glycyl-L-histidyl-L-lysine acetate. The FRTL strain was purified by successive colonial isolations and was found to maintain highly differentiated features (secretion into the culture ...

Thyroid cancer is the commonest endocrine malignancy and is the second most common cancer affecting young females in Oman. The diagnosis of Papillary Thyroid Carcinoma (PTC) is based primarily on histologic architecture and nuclear morphology in routine Haematoxilin and Eosin (H & E) stained slides. Whenever in doubt, immunohistochemistry may be helpful. This retrospective study included 115 ca...

Speculation as to the functions of the thyroid glands has taken two main directions: some suppose that these organs elaborate an internal secretion which is of itself necessary for certain processes of metabolism, while others think that their chief function is to neutralize poisonous substances originating in the body (“enterotoxines”) or introduced into it from without (iodine, for example). ...

Thyroids that did not show any histopathological evidence of disease were collected at necropsy from 107 patients who did not have any history of endocrine disease. Thyroid volume increases with age during childhood and adolescence, remains stable in younger adults, and declines in older subjects. There was no simple mathematical function relating thyroid volume with age: robust smooth curve fi...

The term "parafollicular cell" was named by NONIDEZ (1932) for a special cell type different from the ordinary follicular cells in the dog thyroid gland. The parafollicular cells occur along the basal surface of the follicular epithelium in most mammalian thyroids, and never face the colloid-containing follicular lumen. Morphological studies have been carried out by many investigators, but the ...

BACKGROUND Due to its use of ionising radiation, the field of nuclear medicine is a unique and significant part of medical diagnostics and patient treatment. The aim of this study was to assess the internal exposure of nuclear medicine employees to radioiodine 131I and technetium 99mTc as well as to assess the external exposure doses. MATERIAL AND METHODS The radioiodine 131I and technetium 9...

Ten percent of fine-needle aspirations (FNAs) of the thyroid are deemed "indeterminate" or "suspicious" for malignancy by the cytopathologist, but most of these lesions are benign. Therefore, additional markers of malignancy may prove to be a useful adjunct. The catalytic component of telomerase, human telomerase reverse transcriptase (hTERT), has been found to be reactivated in immortalized ce...

The capacity of 4DCT to quantify organ motion is beyond conventional 3DCT capability. Local control could be improved. However we are unaware of any reports of organ dose measurements for helical 4DCT imaging. We therefore quantified the radiation doses for helical 4DCT imaging. Organ and tissue dose was measured for thoracic and abdominal 4DCT in helical mode using an adult anthropomorphic pha...