electrospinning is a method of nanofiber filter media production. by this method, it is possibleto produce media with nanofiber in the range of nanometer to micrometer. nanofibrous media provide a large specific surface area in a finite volume thus they are suitable for filtration applications. in this study, nanofiber non-woven membranes production of nylon-6 by electrospinning method is inves...

Objective(s): Polymeric nanofiber has a huge potential for a various biomedical applications such as wound healing and orthopedic implant. Since most of the future applications of therapeutic nanofiber are interacting with human blood components, it is important to investigate hemocompatibility. Methods: In this study, nanofibers with antibacterial properties were synthesizedby elec...

Cartilage defects are a major health problem. Tissue engineering has developed different strategies and several biomaterial morphologies, including natural-based ones, for repairing these defects. We used electrospun polycaprolactone (PCL) and starch-compounded PCL (SPCL) nanofiber meshes to evaluate extracellular matrix (ECM) formation by bovine articular chondrocytes (BACs). The main aim of t...

OBJECTIVES Various methods for repairing bone defects are presented. Cell therapy is one of these methods. Bone marrow stromal cells (BMSCs) seem to be suitable for this purpose. On the other hand, lots of biomaterials are used to improve and repair the defect in the body, so in this study we tried to produce a similar structure to the bone by the chitosan and hydroxyapatite. MATERIALS AND ME...

Using a stainless steel mesh as a template collector, electrospun nanofiber meshes with well-tailored architectures and patterns were successfully prepared from biodegradable poly (epsilon-caprolactone) (PCL). It was found that the resulting PCL nanofiber (NF) meshes had similar topological structures to that of the template stainless steel mesh. Such PCL nanofiber meshes (NF meshes) had improv...

Staphylococcus aureus is a virulent pathogen and a major causative agent of superficial and invasive skin and soft tissue infections (SSSTIs). Antibiotic resistance in S. aureus, among other bacterial pathogens, has rapidly increased, and this is placing an enormous burden on the health care sector and has serious implications for infected individuals, especially immunocompromised patients. Alt...

Herein, a robust method to fabricate expanded nanofiber scaffolds with controlled size and thickness using a customized mold during the modified gas-foaming process is reported. The expansion of nanofiber membranes is also simulated using a computational fluid model. Expanded nanofiber scaffolds implanted subcutaneously in rats show cellular infiltration, whereas non-expanded scaffolds only hav...