BACKGROUND 6',7'-Dihydroxybergamottin is a furanocoumarin that inhibits CYP3A4 and is found in grapefruit juice and Seville orange juice. Grapefruit juice increases the oral bioavailability of many CYP3A4 substrates, including cyclosporine (INN, ciclosporin), but intestinal P-glycoprotein may be a more important determinant of cyclosporine availability. OBJECTIVES To evaluate the contribution...

Studies were conducted to evaluate the combined effects of spontaneous fermentation and amylase-rich flours (ARF) on some nutritive value, functional and viscoelastic properties of cowpea-fortified nixtamalized maize. A 2 x 3 x 3 factorial design, with fermentation medium, fermentation time and ARF level, was performed. The blends were fermented for the specific times and analysed for their tit...

OBJECTIVES This study investigated the titratable acidity and erosive potential of acidic agents on the microhardness and surface micromorphology of four restorative materials. METHODS Forty-seven discs of each restorative material; metal-reinforced glass ionomer cement (Ketac-S), resin-modified glass ionomer cement (Fuji II LC), resin composite (Filtek Z250) and amalgam (Valiant-Ph.D.), 12 m...

BACKGROUND We previously showed, in healthy, middle-aged, moderately overweight men, that orange juice decreases diastolic blood pressure and significantly improves postprandial microvascular endothelial reactivity and that hesperidin could be causally linked to the observed beneficial effect of orange juice. The objective was to determine the effect of chronic consumption of orange juice on th...

BACKGROUND Vitamin D has been added to calcium-fortified orange juice. It is unknown whether vitamin D is as bioavailable from orange juice as it is from supplements. OBJECTIVES The objective was to compare the bioavailability of vitamin D(2) and vitamin D(3) from orange juice with that from vitamin D(2) and vitamin D(3) supplements. A secondary aim was to determine which form of vitamin D is...

This in vitro study sought to evaluate nine different sport and energy drinks (B Star Energy drink, London Best Energy Drink, Hippo Energy drink, Lucozade Boost Energy fast, Hype Energy, Vita 500 Energy drink, Lucozade Sport, Power horse Energy drink and Red Bull Energy drink) in terms of initial pH and titratable acidity. Initial pH was measured in triplicate for the nine beverages. The titrat...

Organic acid accumulation in the vacuole of juice cells of citrus fruits is a developmentally regulated process, the degree and timing of which varies greatly among species and varieties and is highly susceptible to environmental conditions (Clements, 1963; Ting and Vines, 1966; Vandercook, 1977). Total titratable acidity of the fruit juice of the acidless pummelo 2240 (Citrus maxima [Burm.] Me...