In response to high-profile attacks that exploit hash function collisions, software vendors have started to phase out the use of MD5 and SHA-1 in third-party digital signature applications such as X.509 certificates. However, weak hash constructions continue to be used in various cryptographic constructions within mainstream protocols such as TLS, IKE, and SSH, because practitioners argue that ...

Several methods to conduct single-tree inventories using airborne laser scanning (ALS) have been proposed, and even terrestrial laser scanning (TLS) has recently emerged as a possible tool for the collection of forest inventory data. In the present study, a novel methodological framework for a combined use of ALS and TLS in an inventory was tested and compared to a method without the use of TLS...

DNA damage blocks the progression of the replication fork. In order to circumvent the damaged bases, cells employ specialized low stringency DNA polymerases, which are able to carry out translesion synthesis (TLS) past different types of damage. The five polymerases used in TLS in human cells have different substrate specificities, enabling them to deal with many different types of damaged base...

BACKGROUND Tumor lysis syndrome (TLS) is a severe, life-threatening complication that typically occurs in highly proliferative malignancies. Although TLS is unusual in multiple myeloma (MM), it is still associated with significant morbidity. Bortezomib has been widely used for the treatment of MM with encouraging results, but TLS seems to occur more frequently in patients with MM receiving bort...

In this paper, we analyse the Transport Layer Security (TLS) protocol (in particular, bilateral TLS in public-key mode) within the strand spaces setting. In [BL03] Broadfoot and Lowe suggested an abstraction of TLS. The abstraction models the security services that appear to be provided by the protocol to the high-level security layers. The outcome of our analysis provides a formalisation of th...

In order to searching the possible pathogenesis of amyotrophic lateral sclerosis (ALS), we examined the expression and distribution of FUS/TLS protein in the different anatomic regions, segments and neural cells of adult spinal cord at the different stages of the SOD1 wild-type and G93A transgenic mice using the fluorescent immunohistochemistry. Result revealed that, in the SOD1 wild-type mice,...

TLS was designed as a transparent channel abstraction to allow developers with no cryptographic expertise to protect their application against attackers that may control some clients, some servers, and may have the capability to tamper with network connections. However, the security guarantees of TLS fall short of those of a secure channel, leading to a variety of attacks. We show how some wide...

BACKGROUND Several studies have implicated a role of inflammation in the pathogenesis of lung damage in idiopathic pulmonary fibrosis (IPF). Parenchymal lung damage leads to defects in mechanics and gas exchange and clinically manifests with exertional dyspnea. Investigations of inflammatory cells in IPF have shown that eosinophils, neutrophils and CD8+ TLs may be associated with worse prognosi...

Tumor lysis syndrome (TLS) is an important oncological emergency that is usually observed with hematological malignancies and rarely with solid tumors. It can be induced either by therapy or spontaneously. Radiotherapy-induced TLS has been rarely reported in the literature. Here we present a patient with a diagnosis of metastatic prostate cancer and chronic lymphocytic leukemia complicated with...

A novel parallel method for determining an approximate total least squares (TLS) solution is introduced. Based on domain distribution, the global TLS problem is partitioned into several dependent TLS subproblems. A convergent algorithm using the parallel variable distribution technique (Ferris and Mangasarian, 1994) is presented. Numerical results support the development and analysis of the alg...