Background: Knowledge of the normal tooth eruption patterns is essential for the identification and appropriate treatment of deviations in eruption that may endanger physiologic development. A delay in time between the exfoliation of a deciduous tooth and the eruption of its permanent successor may be related to a disorder known as dental retention. This occurs when tooth eruption does not occu...

The semidominant gene 'crooked' (Cd) in the mouse produces anomalies of the axial skeleton (resulting in a crooked tail), microphthalmia and dental abnormalities, including small molars with simplified cusp patterns that are equivalent to patterns passed through during normal morphodifferentiation. A series of embryonic litters from Cd/+ xCd/ + matings was used to investigate the embryological ...

Caries is caused by bacterial acid production in tooth plaque, which can cause deep localized lesions if it remains too near the tooth for any length of time. If left the bacteria then may penetrate the tooth further and progress into the soft pulp tissue. Untreated dental caries can lead to incapacitating pain, potential tooth loss and loss of dental function. The development and progression o...

undoubtedly, tooth decay is still one of the most significant problems in human communities. tooth decay is defined as a microbial disease that causes demineralization of hard tissues and degradation of organic components of teeth. although there are various theories on etiology of dental caries, miller’s acidogenic theory (1890) and gottileb’s proteolitic theory (1933) have gained the most cre...

rapidly evolving implantation and alveolar ridge reconstruction techniques created a new area in modern dentistry where tooth loss is no longer a problem. endless variations of implant’s length, diameter, surface, and design along with autogenous, alogenous, aloplastic, or xenogenous bone substitutes made it possible to recreate physiological occlusion, esthetic and masticatory function. howeve...

Although preventive measures have reduced caries, premature loss of pulpally involved primary teeth remains a common problem. The resultant mesial drift of the permanent teeth frequently leads to malocclusion. Retention of the pulpally involved primary tooth to preserve arch space is preferable to space maintenance if the tooth can be restored to normal function and is free of pathology. Additi...

Tooth agenesis is the failure of tooth bud development, causing definitive absence of the tooth. It is the most common dental anomaly, affecting up to one-quarter of the general population. The main cause is related to abnormal function of specific genes which play key roles during odontogenesis, particularly MSX1 and PAX9. MSX1 is a transcription factor highly expressed in the mesenchyme of...