نتایج جستجو برای: topical administration

تعداد نتایج: 285411  

2010

Resistance not limited to P. acnes. Researchers reviewed studies on the use of antibiotics in acne vulgaris over nearly a 50-year period and found that both correct and incorrect use of antibiotics for acne can promote antimicrobial resistance. Among factors contributing to this resistance are antibiotic monotherapy, long-term administration of antibiotics, and the administration of antibiotics...

2005
Ji-Seon Son Sang-Kyi Lee

Topical phenylephrine, an agent used to facilitate nasotracheal intubation and prevent nasal mucosal bleeding, can cause severe hypertension in some patients, secondary to its stimulation of alpha-adrenergic receptors. Moreover, a high incidence of pulmonary edema is found in patients whose phenylephrine administration is followed by treatment with beta-blocking agents. We report a case of acut...

2016
Kaoru Araki-Sasaki Osamu Katsuta Hidetoshi Mano Takashi Nagano Masatsugu Nakamura

BACKGROUND To determine the most effective route of administration of corticosteroids in the treatment of ocular surface disease, by characterizing the difference between oral prednisolone and topical dexamethasone administration using an animal model. METHODS Pharmacokinetic analyses determined the corticosteroid concentrations in the normal ocular tissues of rabbits after oral or topical ad...

Iran Jahanbin, , Nasrin Sharifi, , Parvin AzarHooshang, , Shirin Rahnema, , دوکوهکی, رویا ,

  Background and Aim: One of the most important functions of nurses, which require preparation and powerful scientific background, skill in decision making and careful attention to drug laws is administration of the drugs to the patients. The aim of the present study was to evaluate the knowldege and practice of the student nurses about drugs by OSCE method at the end of the third year of their...

Journal: :Skin pharmacology and physiology 2007
P Palombo G Fabrizi V Ruocco E Ruocco J Fluhr R Roberts P Morganti

BACKGROUND The skin is exposed to numerous environmental assaults that can lead to premature aging. Of these agents, perhaps none is more ubiquitous than the ultraviolet (UV) wavelengths of sunlight. The primary immediate defense against environmental skin damage is the antioxidant capacity of the skin. However, this defense system can be compromised by moderate exposure to UV light. Therefore,...

Journal: :European journal of ophthalmology 2007
H Sakamoto M Sakamoto Y Hata T Kubota T Ishibashi

PURPOSE To investigate the aqueous and vitreous penetration of levofloxacin, the drug was administered topically and/or orally to patients undergoing vitrectomy. METHODS Thirty-six patients undergoing initial vitrectomy with phacoemulsification and aspiration (PEA) were enrolled, and were divided randomly into three groups. Group 1 was treated with topical application of levofloxacin (three t...

Journal: :Pharmacological reviews 2003
Jana Sawynok

Acute nociceptive, inflammatory, and neuropathic pain all depend to some degree on the peripheral activation of primary sensory afferent neurons. The localized peripheral administration of drugs, such as by topical application, can potentially optimize drug concentrations at the site of origin of the pain, while leading to lower systemic levels and fewer adverse systemic effects, fewer drug int...

Journal: :Dermatology 2009
Masaru Honma Hidetoshi Takahashi Michiharu Horikawa Hajime Iizuka

these lesions improved and worsened cyclically along with buserelin acetate administration, the symptoms were relatively easily controlled with a topical steroid and no arthritis associated with SAPHO syndrome was apparent during all courses. Case 2 is that of a 34-year-old Japanese woman who presented with pustules on her palms and soles ( fig. 1 E). She noticed persistent palmar pustules and ...

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