The first total synthesis of a tetracyclic marine pyridinium alkaloid hinged on recent advances in chemoselectivity management: While many classical methods failed to afford the perceptively simple pyridine-containing core target, nickel/iridium photoredox dual catalysis allowed critical C−C bond be formed good yield. Likewise, ring closing alkyne metathesis (RCAM) worked well presence unhinder...

The aim of the present study was to investigate the hypolipidemic and antioxidant potential of ephedra extractions in diet-induced hyperlipidemic mice. Mice were fed a diet high in fat to establish the hyperlipidemic model. A total of 48 mice were randomly divided into six groups, which included the normal control, model control, positive control, ephedra alkaloid, ephedra polysaccharide and ep...

The effect of salinity on growth, photosynthetic pigment content, and alkaloid secondary metabolite accumulation were studied in an economically important medicinal plant, Catharanthus roseus (L.) G. Don., under pot culture conditions. Plants were treated with different concentrations of NaCl, (e.g. 50 and 100 mM) 30, 45, 60, and 75 days after sowing (DAS). The plants were uprooted randomly 90 ...

The value of ephedrine as a therapeutic agent has been appreciated for some years but little attention has been paid to its dextrorotatory isomer pseudo-ephedrine. This latter alkaloid occurs in large quantities in the Indian species of ephedra, most of the specimens containing a proportion of 50 per cent, of the total alkaloid content. Lieut.-Col. R. N. Chopra, i-M.s., and his collaborators of...

Motivation exists to develop tobacco cultivars with reduced nicotine content for the purpose of facilitating compliance with expected tobacco product regulations that could mandate the lowering of nicotine levels per se, or the reduction of carcinogenic alkaloid-derived tobacco specific nitrosamines (TSNAs). A berberine bridge enzyme-like (BBL) gene family was recently characterized for N. taba...