Scientific literature shows that inflammation and oxidative stress contribute in the pathogenesis of atherosclerosis. The oxidative stress is the consequence of an imbalance between the free radical generation and elimination. One source of free oxygen radicals is cyclooxygenase (COX)-2 and, therefore, inhibiting the activity of this enzyme is likely to reduce oxidative stress. In the present s...

Association of oxidative stress and serum prolidase activity (SPA) has been reported in many chronic diseases. The study was aimed at evaluating the correlation of glucose and creatinine to SPA and oxidative stress in patients with diabetic nephropathy (DN) and end stage renal disease (ESRD) concerned with T2DM. 50 healthy volunteers, 50 patients with T2DM, 86 patients with DN, and 43 patients ...

BACKGROUND Assessment of asthma with a control test has been suggested as a relevant approach in recent years. However, no biomarker of systemic inflammation has been included in the assessment of asthma control. OBJECTIVE To evaluate plasma paraoxonase (PON1), total oxidant status (TOS), and total antioxidant status (TAS) levels in children with asthma according to the disease control, and t...

BACKGROUND We aimed to investigate the effects of general, spinal and epidural anesthesia on fetal total antioxidant status (TAS) and total oxidant status (TOS), and oxidative stress index (OSI) during elective cesarean section in this study. MATERIALS AND METHODS Forty-seven parturients scheduled for elective cesarean section were randomly allocated into three groups: Group spinal (n = 15), ...

Objective: To evaluate the glutathione (GSH), lipid peroxidation, total antioxidant status levels (TAS), and liver function parameters such as serum aspartate transaminase (AST) and serum alanine transaminase (ALT) in South Indian hypertensive patients before and after olmesartan and labetalol treatment. Methods: Total 69 subjects were selected for the study. Out of 69 subjects, 29 were healthy...

Our aim was to examine some parameters of oxidative status, gelatinases, and their inhibitors and to evaluate their interrelationships in subjects with metabolic syndrome (MS). We enrolled 65 MS subjects, subdivided according to the presence or not of diabetes mellitus. We examined lipid peroxidation (expressed as thiobarbituric acid reacting substances, TBARS), protein oxidation (expressed as ...

OBJECTIVE In living organisms, there is a balance between the oxidant and antioxidant systems. Reactive products continuously formed by exogenous and endogenous sources are rendered harmless by the antioxidant system. Oxidative stress is an etiological factor in aging and the development of various diseases. In the present study, the aim was to investigate the effects of meal frequency and calo...

Objective: We try to evaluate total oxidant status (TOS), antioxidant (TAS) and oxidative stress index (OSI) in patients with recurrent aphtous stomatitis (RAS) our study. Methods: A of 40 patients, 23 female 17 male, a mean age 29, who applied the dermatology outpatient clinic complaint oral ulcers were diagnosed RAS 49 healthy controls, 33 16 24, included Results: The TOS OSI values group sta...