including prick (epicutaneous) with a mix of Aspergillus species and if negative, intradermal at 1000 PNU/mL, Aspergillus fumigatus (Af). Sera were analyzed for total IgE (elevated is $417 kU/L) by Phadia ImmunoCap, anti-Af IgE and anti-Af IgG (ABPA range $ 2.0) ELISA, and precipitating antibodies. HRCT of the lungs was ordered next if serology was positive (diagnostic criteria for ABPA require...

including prick (epicutaneous) with a mix of Aspergillus species and if negative, intradermal at 1000 PNU/mL, Aspergillus fumigatus (Af). Sera were analyzed for total IgE (elevated is $417 kU/L) by Phadia ImmunoCap, anti-Af IgE and anti-Af IgG (ABPA range $ 2.0) ELISA, and precipitating antibodies. HRCT of the lungs was ordered next if serology was positive (diagnostic criteria for ABPA require...

Monitoring free serum IgE in severe asthma patients treated with omalizumab. 2 Omalizumab is effective in allergic and nonallergic patients with nasal polyps and asthma. 2 Effects of adding omalizumab, an anti-immunoglobulin E antibody, on airway wall thickening in asthma. 3 A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study. 4 Reduction of total Ig...

Bullous pemphigoid (BP) is an autoimmune blistering disease mediated by autoantibodies targeting BP180 (type XVII collagen). Patient sera and tissues typically have IgG and IgE autoantibodies and elevated eosinophil numbers. Although the pathogenicity of the IgE autoantibodies is established in BP, their contribution to the disease process is not well understood. Our aims were two-fold: 1) To e...

Serum IgE levels and the expression of low affinity receptor for IgE (Fc epsilon RII/CD23) are increased in cutaneous leishmaniasis. The ligation of CD23 receptor by IgE-anti-IgE immune complexes results in nitric oxide (NO) production, which is a critical leishmanicidal factor. Human monocytes/macrophages express Fc epsilon RII/CD23 after activation with IFN-gamma and IL-4. In the present stud...

IgE, and atopy. Results: We measured the total serum IgE of 155 children. The number of obese and normal weight children with family history of atopic disease who had high level of total serum IgE were 30 and 25 respectively, whereas these children who had normal level of total serum IgE were 6 and 15 respectively [OR 1⁄4 1.9 (95% CI 0.9-3.9)]. On the other hand, obese and normal weight childre...

Background. There is little knowledge of the causes for raised serum total immunoglobulin E (IgE) in children. We investigated the association between perinatal, socioeconomic, demographic, clinical, paraclinical, and early life factors, and total serum IgE. Methods. In a random sample of 7-17 year old children, data on possible risk factors were collected using a questionnaire and total serum ...

IgE, and atopy. Results: We measured the total serum IgE of 155 children. The number of obese and normal weight children with family history of atopic disease who had high level of total serum IgE were 30 and 25 respectively, whereas these children who had normal level of total serum IgE were 6 and 15 respectively [OR 1⁄4 1.9 (95% CI 0.9-3.9)]. On the other hand, obese and normal weight childre...