Loss of function and subsequent spontaneous recovery after ischaemic stroke are associated with functional and structural alterations in brain tissue. Acute functional tissue damage involves distortion of key metabolic processes, such as oxidative glycolysis and neurotransmittermetabolism.Nevertheless, initially perturbedmetabolismmay be restored at later stages, e.g. in perilesional areas, whi...

ONE ofthe grounds on which disturbance of glycolysis has been assumed to be responsible for experimentally induced degeneration of the retina is the observation recorded by Noell (1951) that injection of sodium iodoacetate abolishes the electric response of the retina much more markedly in mammals than in other species. This finding is suggestive in view of the fact that the mammalian retina is...

AIMS The synthesis of ATP in the liver of the chronic ethanol consumer is suppressed, particularly if the tissue becomes hypoxic. Moreover, the perivenous region of the liver lobule becomes even more oxygen deficient as a result of ethanol consumption. Synthesis of ATP in the perivenous region of the lobule may be depressed in the chronic ethanol consumer due to decreases in both mitochondrial ...

Exposure of Ehrlich ascites tumor cells to the polyanion dextran sulfate altered the permeability of the plasma membrane resulting in decreased glycolysis and respiration, enhanced permeability to Rb+ and adenosine 5'-triphosphate, and increased staining by erythrosin B. The inhibition of respiration was reversed by the addition of inorganic phosphate, whereas restoration of glycolysis required...

Objective: In this study, we aimed to determine the independent predictive parameters of overall survival (OS) ofpatients with inoperable pancreatic ductal adenocarcinoma (PDAC) and investigate whether these parameterscan be used as potential biomarkers shape precision medicine practices for PDAC patients.Material Methods: The clinical pathological data patients who were diagnosed inoperablepan...

PURPOSE Imaging features of sinusoidal obstruction syndrome (SOS), an increasingly common drawback of chemotherapy, were evaluated via 18F-fluorodeoxyglucose (FDG) positron emission tomography computed tomography (PET/CT). EXPERIMENTAL DESIGN This retrospective study was approved by our Institutional Review Board, with a waiver of informed consent. FDG PET/CT studies of 35 patients (male, 24;...

Aim: It was aimed to evaluate the prognostic role of primary tumor metabolic-volumetric parameters 18F-Fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) in resectable tongue squamous cell carcinoma (TSCC).Material and Method: The imaging findings 44 TSCC patients (23 females, 21 males, mean age: 58±12 years) with tumors who underwent 18F-FDG PET/CT for stagi...