The interacting effects of time of exposure and concentration as factors in cytotoxicity were compared for glutaraldehyde and formaldehyde. Cells from a human fibroblast cell line (WI-38) grown to confluence in 24-well trays were exposed to a range of concentrations of each agent, for periods of 4 to 24 hr. Cytotoxicity was measured by its effects on mitochondrial dehydrogenase activity, as ass...

The graft copolymer of locust bean gum (LBG) and acrylamide has been synthesized by microwave assisted method using potassium persulphate (KPS) as an initiator in aqueous medium. Different reaction parameters such as time, initiator concentration, monomer concentration, polymer concentration, and microwave power were studied to get maximum graft copolymer. The grafted copolymer was characterize...

Alpha-linolenic acid and linoleic acid isolated from Ulva fasciata showed toxic effects on red tide phytoplankters in a concentration-dependent manner. Among six species tested, raphidophycean flagellate Heterosigma akashiwo was the most susceptible to these fatty acids, and 50% lethal concentrations (LC50) of alpha-linolenic acid and linoleic acid were estimated to be 0.58 and 1.91 microg/ml r...

There are two clinical situations in which establishing the diagnosis of a toxic adenoma or toxic multinodular goiter is more difficult. First, the autonomously functioning tissue may be sufficiently diffuse that it is difficult to differentiate a toxic multinodular goiter from Graves' disease by thyroid scintigraphy alone. When it is important to distinguish these disorders, a high serum conce...

The aim of study was to integrate chemical analyses and toxicity bioassays in order to assess the environmental risk connected with the presence of trace elements in the sediments. This study examined the ecological significance of trace elements in bottom sediments by applying a set of complementary sediment quality assessment methods sediment quality guidelines (SQGs) (mean probable effect co...

approved: K. S. Pilcher In this study of toxigenic and non -toxigenic strains of Clostridium botulinum type E, attempts were made to induce toxin production in non -toxigenic cultures by exposure to mutagenic agents and to differentiate the organisms by immunodiffusion. First, cultures of non -toxic Cl. botulinum type E were exposed to various mutagenic agents in an attempt to produce toxigenic...

The toxicity of oils can be understood using the concept of toxic potential, or the toxicity of each individual component of the oil at the water solubility of that component. Using the target lipid model to describe the toxicity and the observed relationship of the solubility of oil components to log (Kow), it is demonstrated that components with lower log (Kow) have greater toxic potential th...

Penicillin, the first antibiotic of clinical importance to be discovered, is in many ways the best. Against most pathogenic species of Gram-positive bacteria and Gramnegative cocci a concentration of 0.02 ptg./ml.t or less inhibits growth and a concentration not much higher is actively bactericidal. Moreover, apart from hypersensitivity reactions, penicillin is probably the least toxic of the a...

Distillery effluent discharged as wastewater contains various toxic chemicals that can contaminate water & soil and may affect the common crops by using this water for agriculture irrigation. A laboratory work was undertaken to assess the co-relation between treated distillery effluent concentration and seed germination by using different concentration of distillery effluent like 0%, 25%, 50%, ...

Analytical techniques for the determination of polychorinated dibenzo-p-dioxins (PCDD), polychlorinated dibenzofurans (PCDF) and dioxin-like PCBs (DLPCB) are reviewed. The focus of the review is on recent advances in methodology and analytical procedures. The paper also reviews toxicology, the development of toxic equivalent factors (TEF) and the determination of toxic equivalent quantity (TEQ)...