the Society of toxicology (StOx), India, and Safety and environmental Assurance Centre (SeAC), Unilever, organized a one day symposium on “Novel Strategies for Toxicological Risk Assessments” on September 4, 2013 at Unilever R&D Centre, Bangalore, India. As animal testing for safety assessment of cosmetic ingredients and products is facing a likely ban in India, there is an increasing need to d...

ii DISCLAIMER The use of company or product name(s) is for identification only and does not imply endorsement by the Agency for Toxic Substances and Disease Registry. This public law directed the Agency for Toxic Substances and Disease Registry (ATSDR) to prepare toxicological profiles for hazardous substances which are most commonly found at facilities on the CERCLA National Priorities List an...

OBJECTIVE To analyze the toxicological risk of exposure to ozone (O3) and fine particulate matter (PM2.5) among schoolchildren.. METHODS Toxicological risk assessment was used to evaluate the risk of exposure to O3 and PM2.5 from biomass burning among schoolchildren aged six to 14 years, residents of Rio Branco, Acre, Southern Amazon, Brazil. We used Monte Carlo simulation to estimate the pot...

Due to the abundance of nanomaterials in medical devices and everyday products, toxicological effects related to nanoparticles released from these materials, e.g., by mechanical wear, are a growing matter of concern. Unfortunately, appropriate nanoparticles required for systematic toxicological evaluation of these materials are still lacking. Here, the ubiquitous presence of surface ligands, re...

Arsenic (As) pollution, a potential threat for human health, in vegetables is one of the primary sources As intake by body. In Pot Experiment, content, physiological index and antioxidant enzyme activity radish were determined. The results demonstrated that order concentration tissues was roots > stems leaves. Organic selenium (Se) can inhibit absorption arsenic more effectively than inorgan...

Strontium (Sr) is an element of toxicological concern due to its close chemical proximity Ca. In this work, Sr in sea salts collected from China and South Korea was analyzed by laser‐induced breakdown spectroscopy (LIBS). The precision could be improved using multiple filter‐paper sampling intensity normalization a weak Na I line as reference signal. analyte signal variation between pieces well...

Transformation products usually differ in environmental and toxicological properties compared to the parent contaminants, thus causing potential and unknown environmental risks. To elucidate differential chiral recognition of the aryloxypropanoate herbicide quizalofop ethyl (QE) and its primary product (quizalofop acid, QA), their enantiomeric separation and toxicological impacts to two freshwa...

BACKGROUND Hematologic and biochemical analytes of Sprague-Dawley rats are commonly used to determine effects that were induced by treatment and to evaluate organ dysfunction in toxicological safety assessments, but reference intervals have not been well established for these analytes. Reference intervals as presently defined for these analytes in Sprague-Dawley rats have not used international...

OBJECTIVE To review the available evidence evaluating the toxicological profiles of electronic cigarettes (e-cigarettes) in order to understand the potential impact of e-cigarettes on individual users and the public health. METHODS Systematic literature searches were conducted between October 2012 and October 2013 using five electronic databases. Search terms such as 'e-cigarettes' and 'elect...

Ginkgo biloba extract (GBE; CASRN 90045-36-6) is a commonly used herbal supplement. A comprehensive toxicological assessment by the NTP identified GBE as hepatotoxic. The constituents of GBE can vary across lots, hence the question arises as to how representative the lot tested by NTP is of other lots of GBE and by extension to what degree the results of the NTP hazard characterization are more...