نتایج جستجو برای: transcription factor 7

تعداد نتایج: 1556118  

Journal: :QJM: An International Journal of Medicine 2021

Abstract Background Type 2 diabetes mellitus (T2DM) is a heterogeneous group of metabolic disorders characterized by the incapability pancreatic beta cells to increase insulin secretion compensate for resistance in peripheral tissues. T2DM multi-factorial disease including several environmental factors with presence genetic predisposition. The transcription factor 7-like-2 gene (TCF7L2) rs79031...

Journal: :Biomedicine 2023

Predisposition to diabetes is attributed a large number of genes. TCF7L2 one the most significant candidate genes among them, and it crucial for beta-cell activity blood glucose regulation. According previous research, has been implicated in T2DM various Indian tribes. Many studies have discovered link between gene variations vulnerability T2DM. These results suggest that changes expression are...

2015
Tiffany Carr Veena Krishnamoorthy Shuyang Yu Hai-Hui Xue Barbara L. Kee Mihalis Verykokakis

Invariant natural killer T cells (iNKT cells) are innate-like T cells that rapidly produce cytokines that impact antimicrobial immune responses, asthma, and autoimmunity. These cells acquire multiple effector fates during their thymic development that parallel those of CD4(+) T helper cells. The number of Th2-type effector iNKT cells is variable in different strains of mice, and their number im...

Journal: :Nature Reviews Genetics 2011

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2011

Journal: :Nucleic Acids Research 2002

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