Artemisinin, isolated from Artemisia annua, is recommended as the preferred drug to fight malaria. Previous research showed that jasmonate (JA)-mediated promotion of artemisinin accumulation depended on light. However, mechanism underlying interaction light and JA in regulating still unknown. We identified a WRKY transcription factor, AaWRKY9, using transcriptome analysis. The glandular trichom...

High uncoupling protein 1 (Ucp1) expression is a characteristic of differentiated brown adipocytes and linked to adipogenic differentiation. Paracrine fibroblast growth factor 8b (FGF8b) strongly induces Ucp1 transcription in white independent adipogenesis. Here, we report that FGF8b other paracrine FGFs act on preadipocytes upregulate via FGFR1-MEK1/2-ERK1/2 axis, Transcriptomic analysis revea...

Diabetic kidney disease (DKD) is the most important microvascular complication of diabetes and leading cause end-stage renal (ESRD) worldwide. The Janus kinase/signal transducer activator transcription (JAK/STAT) signaling pathway, which out balance in context DKD, acts through a range metabolism-related cytokines hormones. JAK/STAT primary node progression DKD. latest research on helps determi...

Artemisia argyi Levl. et Van (A. argyi) is a traditional medicinal plant, which widely used in health, food and medicine. Thujone an important cyclic monoterpene derivative the volatile oil of A. leaves with multiple efficacy. Although thujone synthetic pathway has been preliminarily analyzed very few species, genes related to content remain largely unknown. In this study, we identify candidate...

Abstract Background Myriocin is a natural product with antifungal activity and derived from Bacillus amyloliquefaciens LZN01. Our previous work demonstrated that myriocin can inhibit the growth of Fusarium oxysporum f. sp. niveum (Fon) by inducing membrane damage. In this study, actions against Fon were investigated focus on effects intracellular molecules. Results Analysis DNA binding fluoresc...

Effective cancer therapy requires identification of signaling networks and investigating their potential role in proliferation invasion cells. Among molecular pathways, signal transducer activator transcription 3 (STAT3) has been importance due to its involvement promoting proliferation, cells, mediating chemoresistance. In the present review, our aim is reveal STAT3 pathway bladder (BC), as on...