Iodine is an essential element for thyroid hormone synthesis. The thyroid gland has the capacity and holds the machinery to handle the iodine efficiently when the availability of iodine becomes scarce, as well as when iodine is available in excessive quantities. The latter situation is handled by the thyroid by acutely inhibiting the organification of iodine, the so-called acute Wolff-Chaikoff ...

Aim: In this paper, the related factors of transient hypothyroidism in premature infants were discussed, incidence THOP was observed, and risk analyzed to guide future work. Methods: From January 2017 2018, 117 admitted neonatology Department First Affiliated Hospital Bengbu Medical College selected diagnosed with 48 cases, including 31 males 17 females.< 1 500 g ~ 2 70 > 30 cases; Gestat...

Spermatogenesis and sperm maturation are complex processes which are affected by a myriad of endocrine, paracrine and neural factors. In birds, regulation of testicular and excurrent duct growth, maturation and function are only poorly understood. As the quality and quantity of sperm produced may be altered at any of several points during sexual maturation, spermatogenesis or during extragonada...

Abstract Neonatal screening for congenital primary hypothyroidism (CH) may not distinguish between transient (TCH) and permanent dysfunction (PCH), causing potential overtreatment concerns in affected families. To specify the indication interruption of therapy, we analysed German registry “HypoDok” infants with CH, which oversees 1625 patients from 49 participating centres Germany Austria 1997 ...

Thyroid imaging is indicated to evaluate congenital hypothyroidism during newborn screening or in cases of a palpable thyroid mass in children and adolescents. This pictorial essay reviews the ultrasonography (US) of thyroid diseases in children and adolescents, including normal thyroid gland development, imaging features of congenital thyroid disorders (dysgenesis, [aplasia, ectopy, hypoplasia...

Thyroid hormone is critical for neonatal brain development, and even transient hypothyroidism can cause adverse neurocognitive outcomes. Infants exposed to excess iodine are at risk of developing hypothyroidism, especially those with congenital heart disease (CHD), because they are routinely exposed to excess iodine from intravenous iodinated contrast media and topical antiseptics. The aim of t...

Elevated serum creatine kinase levels are one of the major criteria for the diagnosis of myocardial injury. Noncardiac causes such as muscular and brain damage may also be associated with elevated serum creatine kinase levels. Hyponatremia may induce increased serum creatine kinase in association with rhabdomyolysis or with hypothyroidism. A patient is described where three episodes of hyponatr...