Ganser syndrome continues to be a rare and widely misunderstood condition. While DSM-IV classifies Ganser syndrome as a dissociative disorder, its etiology continues to be debated. There are episodic reports in the literature of Ganser syndrome in patients with head trauma or strokes. However, the mechanisms by which these cerebral insults lead to Ganser syndrome or other dissociative states ar...

Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature ageing disorder that is characterized by accelerated degenerative changes of the cutaneous, musculoskeletal and cardiovascular systems. Mean age at diagnosis is 2.9 years and generally leading to death at approximately 13 years of age due to myocardial infarction or stroke. Orthopedic manifestations of HGPS are multiple and shoulde...

Guillain Barre Syndrome (GBS) is an acute inflammatory polyneuropathy, often characterized by symmetrical weakness and areflexia. It considered to be autoimmune disease triggered previous bacterial or viral infections. Miller Fisher’s syndrome one of the most common variants GBS, it trauma with areflexia, ataxia, ophthalmoparesis. Mortality 1-2% in childhood GBS generally develops due respirato...

Trauma is the major cause of death worldwide. Survival of the major trauma victims can be improved by the principles of damage control surgery. The vicious cycle of trauma triad, namely, hypothermia, coagulopathy and acidosis should be intercepted by the quick abbreviated laparotomy and subsequently physiological imbalance is corrected by secondary resuscitation in the surgical intensive care u...

Trauma is a major public health problem worldwide. Infectious complications, sepsis, and multiple organ dysfunction syndrome (MODS) remain important causes for morbidity and mortality in patients who survive the initial trauma. There is increasing evidence for the role of genetic variation in the innate immune system on infectious complications in severe trauma patients. We describe a trauma pa...