BACKGROUND Preventing diabetic foot problems (DFP) and their associated consequences is a critical in rural regions. The objective is to present an association of non-invasive DFP assessment tools and physiological indicators for early detection among rural cases of diabetes in Taiwan. METHODS Secondary data analysis of 387 participants previously diagnosed with type 2 diabetes was used. The ...

This study was designed to delineate the involvement of phospholipase C (PLC) and phospholipase D (PLD) in transmural pressure control of renin synthesis and secretion. Primary cultures of rat juxtaglomerular (JG) cells were applied to a transmural pressure-loading apparatus for 12 hours, and the renin secretion rate (RSR), active renin content (ARC), and total (active + inactive) renin content...

BACKGROUND AND AIM Despite improvements in surgical revascularisation, limitations like anatomical factors or atherosclerosis limit the success of revascularisation in diabetic patients with critical limb ischaemia. Stem cells were shown to improve microcirculation in published studies. The aim of this study was to evaluate safety, feasibility and efficacy of transplantation of bone marrow deri...

The role of intracellular cAMP and Ca(2+) in the excitation and adaptation of taste responses by HCl was investigated by direct measurement of intracellular pH (pH(i)) in polarized taste receptor cells (TRCs) and by chorda tympani (CT) nerve recordings. Stimulating the tongue with HCl concentrations between 1 and 30 mM caused a dose-dependent increase in CT responses that were insensitive to vo...

The relationship between cell volume and the neural response to acidic stimuli was investigated by simultaneous measurements of intracellular pH (pHi) and cell volume in polarized fungiform taste receptor cells (TRCs) using 2',7'-bis-(2-carboxyethyl)-5-(and-6)-carboxyfluorescein (BCECF) in vitro and by rat chorda tympani (CT) nerve recordings in vivo. CT responses to HCl and CO2 were recorded i...

The relationship between taste receptor cell (TRC) intracellular Ca(2+) ([Ca(2+)](i)) and rat chorda tympani (CT) nerve responses to bitter (quinine and denatonium), sweet (sucrose, glycine, and erythritol), and umami [monosodium glutamate (MSG) and MSG + inosine 5'-monophosphate (IMP)] taste stimuli was investigated before and after lingual application of ionomycin (Ca(2+) ionophore) + Ca(2+),...

One might assume that the Truth and Reconciliation Commission of Canada (TRC) final report1 is about Indigenous peoples in Canada. It is, and it is not. The 528page report, as well as its 94 recommendations, released in June 2015,2 is about and for all Canadians. If you live in Canada, this report is written for you. If you are a health care provider, educator, or leader, this report has specif...

The electromagnetic time-reversal (TR) technique has the characteristics of spatiotemporal focusing in a cavity (TRC), which can be used for pulse compression, thus forming an with high peak power. A time-reversed pulse-compression method single channel compression gain. However, only generate limited This paper proposes novel TR power-combination multichannel TRC to obtain higher power based o...

postexposure rabies vaccination in patients with human immunodeficiency virus with low CD4 ϩ T lymphocyte cell counts. Reply Sir—We thank Drs. Mary and David War-rell [1] for noting the error in the percentage of patients with seroconversion presented in table 2 of our article [2]; the rate should have appeared as 27%, not 7%. On day 7 of the regimens, the levels of neutralizing antibodies (NAb...

• Predicting clinical outcome and response to CRT in patients with HFrEF is complex. Phenomapping unsupervised hierarchical cluster analysis finds 4 phenogroups. The four phenogroups differ characteristics outcomes. terms of mortality after CRT. may help identify who will derive most benefit from approach be improved by other risk markers. Despite having an indication for cardiac resynchronizat...