We read with interest the Article by Mikael Mazighi and colleagues,1Mazighi M Richard S Lapergue B et al.Safety efficacy of intensive bloaod pressure lowering after successful endovascular therapy in acute ischaemic stroke (BP-TARGET): a multicentre, open-label, randomised controlled trial.Lancet Neurol. 2021; 20: 265-274Summary Full Text PDF PubMed Scopus (20) Google Scholar who tested whether...

Introduction A patient/person-reported outcome measure (PROM) is a questionnaire that measures patient’s health self-assessment (PROs), such as pain/wellbeing. HTx Horizon 2020 project supported by the European Union lasting for 5 years from January 2019. The main aim of to create framework Next Generation Health Technology Assessment (HTA) support patient-centred, societally oriented, real-tim...

A magnetic resonance imaging (MRI) study was conducted as part of an intervention study in subjects with amnestic mild cognitive impairment (aMCI) to assess donepezil's treatment effect on brain atrophy. Adults with aMCI were randomly assigned to double-blind treatment with 10 mg/day donepezil hydrochloride or placebo for 48 weeks. Brain MRI scans were acquired at baseline and endpoint. The pri...

evidence acquisition we searched pubmed, google scholar and the cochrane databases for systemic reviews, review articles, meta-analysis and randomized clinical trials up to december 2013. results in this review, the efficacy and safety of the more commonly used cam methods for the treatment of obesity, namely herbal supplements, acupuncture, and non-invasive body-contouring, are briefly discuss...