نتایج جستجو برای: trichuris muris excretory

تعداد نتایج: 6887  

2014
Jonathan Pettitt Lucas Philippe Debjani Sarkar Christopher Johnston Henrike Johanna Gothe Diane Massie Bernadette Connolly Berndt Müller

The organization of genes into operons, clusters of genes that are co-transcribed to produce polycistronic pre-mRNAs, is a trait found in a wide range of eukaryotic groups, including multiple animal phyla. Operons are present in the class Chromadorea, one of the two main nematode classes, but their distribution in the other class, the Enoplea, is not known. We have surveyed the genomes of Trich...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2010
Yasuaki Motomura Waliul I Khan Rami T El-Sharkawy Monica Verma-Gandhu Richard K Grencis Stephen M Collins

Irritable bowel syndrome (IBS) is common in countries where chronic parasitic infestations are endemic. However, the relationship between parasitic infection and IBS is not clear. The aim of this study was to examine whether chronic parasitic infection is accompanied by gut dysfunction and whether the continued presence of the parasite is required for the maintenance of the dysfunction. We used...

2017
B. M. Assas S. E. Levison M. Little H. England L. Battrick J. Bagnall J. T. McLaughlin P. Paszek K. J. Else J. L. Pennock

Infliximab (IFX) has been used repeatedly in mouse preclinical models with associated claims that anti-inflammatory effects are due to inhibition of mouse tumour necrosis factor (TNF)-α. However, the mechanism of action in mice remains unclear. In this study, the binding specificity of IFX for mouse TNF-α was investigated ex vivo using enzyme-linked immunosorbent assay (ELISA), flow cytometry a...

ژورنال: تحقیقات دامپزشکی 2001
دکتر ایرج مؤبدی روح ا... دهقانی سیما راستی عباس درودگر

به منظور شناخت تنوع آلودگیهای کرمی دستگاه گوارش موشهای شهرستان کاشان 120 سر موش ووحشی و خانگی از مناطق کویری و شهری کاشان با تله زنده گیر ، صید گردید و پس از بیهوشی و شناسایی ، تشریح و کرمهای دستگاه گوارش جدا گردید و پس از شمارش و فیکساسیون درفرمالین 10 درصد و رنگ آمیزی با کلیدهای تشخیص شناسلیی گردید . نتایج تحقیق نشان داد 68 سر موش (7/56 درصد) آلوده به کرمهای روده ای بودند و مجموعاً 6 گونه نمات...

Journal: :Infection and immunity 2002
Neil E Humphreys Richard K Grencis

The plethora of changes associated with immunosenescence radically alters virtually all aspects of immune responsiveness. How this transformation effects resolution of an infectious challenge is addressed in this study. A well-established infection model was used; Trichuris muris, a cecum-dwelling helminth, is natural to mice, and infection in different strains results in clearly polarized resp...

2016
Phurpa Wangchuk Mark S Pearson Paul R Giacomin Luke Becker Javier Sotillo Darren Pickering Michael J Smout Alex Loukas

BACKGROUND Whipworms and blood flukes combined infect almost one billion people in developing countries. Only a handful of anthelmintic drugs are currently available to treat these infections effectively; there is therefore an urgent need for new generations of anthelmintic compounds. Medicinal plants have presented as a viable source of new parasiticides. Ajania nubigena, the Bhutanese daisy, ...

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