Triglyceride rich-lipoproteins induce triglyceride accumulation in macrophages, leading to foam cell formation. The correlation between cell triglyceride accumulation and lipoprotein lipase (LPL) secretion in murine macrophages and the role that LPL plays in the accumulation process were examined. LPL secretion is defined as the extracellular LPL activity that accumulates during a 4-hour incuba...

this study was conducted to investigate the effects of different levels of soybean lecithin on performance and blood lipids of broiler chicks. a total of 180 one day old ross 308 broiler chicks were used in a completely randomized design with nine treatments (diets with 0, 0.2, 0.4, 0.6, 0.8, 1, 1.2, 1.4 and 1.6 percent of soybean lecithin) and four replicates for 47 days-rearing period. in ord...

We have studied the accretion of lipids in growing mice. We measured the rates of synthesis and degradation of triglycerides in epididymal fat pads of mice maintained for 44 days on a low-fat, high-carbohydrate diet (I) or a high-fat, low-carbohydrate diet (II). 2H2O was added to the drinking water for 14 days. Rates of incorporation/washout of 2H to/from C1 of triglyceride-glycerol showed that...

Objective: Increased risk of atherosclerotic cardiovascular disease in subjects with type 2 diabetes is linked to elevated levels triglyceride-rich lipoproteins and their remnants. The metabolic effects PCSK9 (proprotein convertase subtilisin/kexin 9) inhibitors on this dyslipidemia were investigated using stable-isotope-labeled tracers. Approach Results: Triglyceride transport the metabolism a...

background dyslipidemia is associated with cardiovascular morbidities and mortality. currently, fasting lipid profile determination is used to monitor treatment response. recently, postprandial lipemia is of increasing interest because of its atherogenic and thrombogenic potential and also was found to be more predictive for cardiovascular diseases. objectives to demonstrate postprandial lipemi...

OBJECTIVE The association between changes in triglyceride concentrations over time and diabetes is unknown. We assessed whether two triglyceride determinations obtained 5 years apart can predict incident type 2 diabetes. RESEARCH DESIGN AND METHODS Triglyceride levels at baseline (time 1) and 5 years later (time 2), followed by subsequent follow-up of 5.5 years, were measured in 13,953 appare...

because the ingestion of some types of dietary fibers has been shown to influence on the lipid and lipoprotein levels, it is possible that chitosan influences on lipid metabolism. in the present study, the effects of chitosan on the serum, liver lipid and lipoprotein concentrations in rat were investigated. serum lipid level in the treatment groups were decreased compared to that of the control...