For six random splits, one-variable models of rat toxicity (minus decimal logarithm of the 50% lethal dose [pLD50], oral exposure) have been calculated with CORAL software (http://www.insilico.eu/coral/). The total number of considered compounds is 689. New additional global attributes of the simplified molecular input line entry system (SMILES) have been examined for improvement of the optimal...

This paper presents the design methodology for the bilingual pronunciation dictionary of sound reference usage, which reflects the cross-linguistic, dialectal, first language (L1) interfered, biological and allophonic variations. The design methodology features 1) the comprehensive coverage of allophonic variation, 2) concise data entry composed of a balanced distribution of dialects, genders, ...

background treatment of helicobacter pylori (h. pylori) as a major cause of gastric diseases is of utmost concern.we aimed to assess efficacy of triple therapy (amoxicillin, clarithromycin and pantoprazole) plus probiotic yogurt (py) on eradication of h.pylori. methods total 102 h. pylori positive patients were divided to 3 groups equally and randomly. for treatment of each group amoxicillin, c...

Spreadsheets are widely used by knowledge workers, especially in the industrial sector. Their methodology enables a well understood, easy and fast possibility to enter data. As filling out a spreadsheet is more accessible to common knowledge workers than defining RDF statements, in this paper, we present a tool which uses the spreadsheet metaphor to enable various kinds of users to easily creat...

A graph G is a triple, consisting of a vertex set V= V(G), an edge set E=E(G) and a map that associates to each edge two vertices (not necessarily distinct) called its end points. A loop is an edge whose end points are equal. Multiple edges are edges having same end points. A simple graph is one having no loops or multiple edges. To any graph, we can associate the adjacency matrix A which is an...

Rotavirus is a major cause of severe, dehydrating childhood diarrhea. VP7, the rotavirus outer capsid glycoprotein, is a target of protective antibodies and is responsible for the calcium-dependent uncoating of the virus during cell entry. We have purified, characterized, and crystallized recombinant rhesus rotavirus VP7, expressed in insect cells. A critical aspect of the purification is the e...

Early thymocytes undergo extensive proliferation after their entry into the thymus, but cellular interactions and cytokines regulating this intrathymic step remain to be determined. We analyzed the effects of various T-cell growth factors and cellular interactions on in vitro proliferation of early CD2'CD3/TCR-CD4-CD8(triple negative [TN]) human thymocytes. Freshly isolated TN cells were then a...

We define the commuting algebra determinant of a finite group action on a finite set, a notion dual to the group determinant of Dedekind. We show that the following combinatorial example is a commuting algebra determinant. Let Bq(n) denote the set of all subspaces of an n-dimensional vector space over Fq. The type of an ordered pair (U, V ) of subspaces, where U, V ∈ Bq(n), is the ordered tripl...