Introduction According to the Consensus Guideline, “therapeutic reference range” (TRR) defines ranges of drug blood concentrations that specify a lower limit below which drug-induced therapeutic response is unlikely occur and an upper above tolerability decreases or improvement ceases. The TRR can be obtained from concentration measurements (trough (pre-dose) plasma under steady-state condition...

We present a 2 × 2 Lax representation for discrete circular nets of constant negative Gauß curvature. It is tightly linked to the 4D consistency of the Lax representation of discrete K-nets (in asymptotic line parametrization). The description gives rise to Bäcklund transformations and an associated family. All the members of that family – although no longer circular – can be shown to have cons...

One of the topologies that can work at high Power and high Quality simultaneously is the DCI-NPC topology. This new topology has new parts and presents new voltage and distortion errors. One of these new elements are the MOSFET parasitic Diodes. These Parasitic-Diodes presents a Recovery Reverse Time (trr) and its distorting effects generates signal and quality losses, and EMI problems. These p...

The phagocyte reduced nicotinamide adenine dinucleotide phosphate oxidase is a multiprotein enzyme that catalyzes the production of microbicidal oxidants. Although oxidase assembly involves association of several membrane and cytosolic oxidase proteins, one of the cytosolic cofactors, p67, appears to play a more prominent role in final activation of the enzyme complex. Based on the importance o...

Abstract To compare fixation deviation and stability with soft contact lens correction device built-in auto-focus system during optical coherence tomography angiography (OCTA). This observational study measured OCTA metrics first correction, followed by removal of lenses, using the at a University Optometry Clinic, Hong Kong. All participants were habitual wearers either low or high myopia. mea...

In recent years, video research has dealt with high-frame-rate (HFR) content. Even though low or standard frame rates (SFR) that correspond to values less than 60 frames per second (fps) are still covered. Temporal conversions applied accompanied compression and, thus, it is of importance observe and detect possible effects typical compressed manipulations over HFR (60 fps+) This paper addresse...

Abstract Injury from motor vehicle accidents remains a leading cause of death in India with increasing number fatalities. Timely delivery lifesaving interventions is critical for survival and restoring physical functioning. As part the Australia Trauma Systems Collaboration, Reception Resuscitation (TRR©)-computerized decision support system was implemented Level 1 Centre order to determine whe...