Firstly, it is controversial to define the second case as tubulointerstitial nephritis (TIN) or TINU syndrome due to lack of either histopathological analysis, or renal failure or uveitis. Despite spontaneous regression of renal findings, it is invalid to diagnose TIN without a biopsy. A similar clinical course may be seen in various other renal disorders related to tubules. It has been reporte...

Implication for health policy/practice/research/medical education: Systemic lupus erythematosus (SLE) is a common multisystemic immunological disorder with protean manifestations. It commonly involves the kidney, which is associated with significant morbidity and mortality. In the kidney, it typically affects glomeruli and blood vessels with secondary involvement of tubulointer-stitial componen...