Abstract It is well-established that kidney cancer or renal cell carcinoma (RCC) occurs more commonly in chronic disease (CKD) than the general population though underlying mechanisms are incompletely understood. Beyond hereditary RCC syndromes; smoking, obesity and hypertension widely known risk factors for RCC, irrespective of CKD. Kidney-specific such as episodes acute injury, nephrolithiasi...

conclusions those with inadequate health literacy had lower kidney knowledge and lower adherence compared to those with adequate health literacy. after controlling for education, health literacy was significantly associated with kidney knowledge and adherence. patients with higher health literacy had higher kidney knowledge and adherence behaviors. in addition, knowledge was a mediator of healt...

recent studies suggested the role of white blood cells (wbcs) in the pathogenesis and complications of type 2 diabetes. increased wbc counts predict mortality in patients with chronic kidney disease (ckd). in this study alterations in wbc subpopulations in diabetic patients with non-dialysis dependent ckd are investigated. this was a cross-sectional study  on 376 participants, including   272 d...

background :attention deficit hyperactivity disorder (adhd) is the most common childhood neurological disorder. this disorder is more prevalent in some chronic diseases. the aim of this study was to investigate adhd in children with early stages of chronic kidney disease (ckd) and to compare it with healthy children.   methods : seventy five 5-16-year-old children with early stages of ckd (stag...

autosomal dominant polycystic kidney disease (adpkd) is an inherited disorder associated with multiple cyst formation in the different organs. development of pancreatic cyst in adpkd is often asymptomatic and is associated with no complication. a 38‑year‑old man with adpkd was presented with six episodes of acute pancreatitis and two episodes of cholangitis in a period of 12 months. various ima...

background contrast-induced nephropathy (cin) is one of the most important complications of angiography in patients with chronic kidney disease (ckd) or diabetes mellitus. the prevention of cin can decrease therapeutic costs and hospital stays. there is controversy in the literature over the preventive effect of statins on cin. objectives this study was designed to evaluate the preventive effec...

Congenital anomalies of the kidney and urinary tract are the major cause of end-stage renal disease in childhood. Children with a solitary functioning kidney form an important sub-group of congenital anomalies of the kidney and urinary tract patients, and a significant fraction of these children is at risk for progression to chronic kidney disease. However, challenges remain in distinguishing p...

BACKGROUND The inflammasome is a complex of proteins in the cytoplasm that consists of three main components: a sensor protein (receptor), an adapter protein and caspase-1. Inflammasomes are the critical components of innate immunity and have been gradually recognized as a critical mediator in various autoimmune diseases; also, their role in chronic kidney disease and acute kidney injury has be...