Philipp Werner1 [email protected] Ayoub Al-Hamadi1 [email protected] Robert Niese1 [email protected] Steffen Walter2 [email protected] Sascha Gruss2 [email protected] Harald C. Traue2 [email protected] 1 Institute for Information Technology and Communications, Otto-von-Guericke University, Magdeburg, Germany 2 Department for Psychosomatic Medicine and Psychothe...

BACKGROUND Children born with reduced congenital renal mass have an increased risk of hypertension and chronic kidney disease in adulthood, although the mechanisms are poorly understood. Similar sequelae occur after fetal uninephrectomy (uni-x) in sheep, leading to a 30% nephron deficit. We hypothesized that renal dysfunction is underpinned by a reduced contribution of nitric oxide (NO) and vas...

Previously, we have shown that fetal uninephrectomy (uni-x) causes hypertension in female sheep by 2 years of age. Whilst the hypertension was not exacerbated by 5 years of age, these uni-x sheep had greater reductions in renal blood flow (RBF). To further explore these early indications of a decline in renal function, we investigated the renal response to a saline load (25 ml/kg/40 min) in 5-y...

Introduction Transcription factors are proteins that regulate gene expression levels by binding to specific short DNA sequences (cisacting elements) in the promoter region of target genes, and enhancing or repressing their transcription rate. Their identification is a key step for the reconstruction of transcriptional regulatory networks. The availability of complete genomes together with prote...

Recent empirical research has shown conclusive advantages of multimodal interaction over speech-only interaction for map-based tasks. This paper describes a mul-timodal language processing architecture which supports interfaces allowing simultaneous input from speech and gesture recognition. Integration of spoken and gestural input is driven by uniication of typed feature structures representin...

A uni-stroke text input strategy for wheel input controls is proposed, such as the wheel controls found on the 5th generation ipod multimedia devices. The popularity of the ipod indicates that the wheel input paradigm is intuitive and usable. The proposed uni-strokes are based on circular motions that follow the contour of the wheel. Spatial mnemonics based on the shape of the alphabetic charac...

The objective of the present study was to determine if patients with COPD who were taking Theo-Dur bid or tid (total dose 400 to 900 mg per day) could be safely switched to Uni-Dur, 800 mg given qd at bedtime. Twenty-eight patients were enrolled in the study, and 23 completed the study. The mean daily dose of theophylline prior to the study was 828 mg, while the mean dose after three weeks of U...