نتایج جستجو برای: urinary ghrelin

تعداد نتایج: 113207  

2016
Sakine Sever Donna L White José M Garcia

Ghrelin is a hormone with multiple physiologic functions, including promotion of growth hormone release, stimulation of appetite and regulation of energy homeostasis. Treatment with ghrelin/ghrelin-receptor agonists is a prospective therapy for disease-related cachexia and malnutrition. In vitro studies have shown high expression of ghrelin in cancer tissue, although its role including its impa...

Journal: :علوم زیستی ورزشی 0
امیر رشیدلمیر دانشجوی دوره دکتری فیزیولوژی ورزشی دانشگاه تربیت مدرس عباس قنبری نیاکی دانشیار گروه تربیت بدنی و علوم ورزشی دانشگاه مازندران فاطمه رهبری زاده استادیار گروه بیوتکنولوژی دانشگاه تربیت مدرس

it has been suggested that ghrelin may play a role in the response of growing hormone (gh) to exercises. the present study was designed to examine the effects of 6 weeks of wrestling and a wrestling–based circuit exercise (wbce) on plasma ghrelin and some glucoregulatory hormones in well-trained wrestlers. 30 well-trained male wrestlers (age 18.5±1.5 and bmi 24.8±6.81) voluntarily participated ...

2012
Michael M. Scott Mario Perello Jen-Chieh Chuang Ichiro Sakata Laurent Gautron Charlotte E. Lee Danielle Lauzon Joel K. Elmquist Jeffrey M. Zigman

The neuronal coordination of metabolic homeostasis requires the integration of hormonal signals with multiple interrelated central neuronal circuits to produce appropriate levels of food intake, energy expenditure and fuel availability. Ghrelin, a peripherally produced peptide hormone, circulates at high concentrations during nutrient scarcity. Ghrelin promotes food intake, an action lost in gh...

Journal: :American journal of physiology. Endocrinology and metabolism 2005
Madhusmita Misra Karen K Miller Kelly Kuo Kathryn Griffin Victoria Stewart Emily Hunter David B Herzog Anne Klibanski

Ghrelin is an orexigenic peptide and a growth hormone (GH) secretagogue. Secretory dynamics of ghrelin have not been characterized in adolescents with anorexia nervosa (AN). We hypothesized that, compared with healthy adolescents, girls with AN would have increased ghrelin concentrations measured over 12 h of nocturnal sampling from increased basal and pulsatile secretion, and endogenous ghreli...

H. Khosravinia H. Nayebzadeh J. Cheraghi M. Taati,

This study was conducted to investigate the possible involvement of the histaminergic system in themediation of ghrelin-induced feeding behavior in broiler chickens. In the trial 1, the effect ofintracerebroventricular (ICV) injection of ghrelin on feed intake was examined in 3-h feed-deprived broilerchickens. In the trials 2 and 3, the chickens were received ICV chlorpheniramine (an H1 recepto...

A Gholamhoseinian Gh.R Moshtaghi-Kashanian M Kor M Sanjari

Introduction: Leptin and Ghrelin are hormones that have been discovered in the last decade and were shown to be involved in appetite and metabolism regulation and body weight. Thyroid hormones are also    involved in general metabolism and changes in their circulating levels bring about changes in appetite and body weight. Results of animal and human studies regarding Leptinlevel and its re...

Journal: :Endocrine journal 2005
Ichiro Yokota Seiko Kitamura Hiroshi Hosoda Yumiko Kotani Kenji Kangawa

The octanoylation of Ser3 is essential for the biological function of ghrelin. We examined the concentrations of the n-octanoylated active-form ghrelin in cord and neonatal blood using an RIA system that specifically recognized n-octanoylated ghrelin, as well as a system that measured the total ghrelin concentration. Plasma levels of active ghrelin in cord blood ranged from 7.7 to 38.4 pmol/l a...

2010
Ichiro Sakata Takafumi Sakai

Ghrelin is 28-amino-acid peptide that was discovered from the rat and human stomach in 1999. Since the discovery of ghrelin, various functions of ghrelin, including growth hormone release, feeding behavior, glucose metabolism, memory, and also antidepressant effects, have been studied. It has also been reported that ghrelin in the gastrointestinal tract has an important physiological effect on ...

Journal: :Molecular biology of the cell 2007
Nicoletta Filigheddu Viola F Gnocchi Marco Coscia Miriam Cappelli Paolo E Porporato Riccardo Taulli Sara Traini Gianluca Baldanzi Federica Chianale Santina Cutrupi Elisa Arnoletti Corrado Ghè Alberto Fubini Nicola Surico Fabiola Sinigaglia Carola Ponzetto Giampiero Muccioli Tiziana Crepaldi Andrea Graziani

Ghrelin is an acylated peptidyl gastric hormone acting on the pituitary and hypothalamus to stimulate appetite, adiposity, and growth hormone release, through activation of growth hormone secretagogue receptor (GHSR)-1a receptor. Moreover, ghrelin features several activities such as inhibition of apoptosis, regulation of differentiation, and stimulation or inhibition of proliferation of several...

Journal: :Biochimica et biophysica acta 2010
Edith Staes Pierre-Antoine Absil Laurence Lins Robert Brasseur Magali Deleu Nathalie Lecouturier Virginie Fievez Anne des Rieux Marie-Paule Mingeot-Leclercq Vincent Raussens Véronique Préat

The O-octanoylation of human ghrelin is a natural post-translational modification that enhances its binding to model membranes and could potentially play a central role in ghrelin biological activities. Here, we aimed to clarify the mechanisms that drive ghrelin to the membrane and hence to its receptor that mediates most of its endocrinological effects. As the acylation enhances ghrelin lipoph...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید