INTRODUCTION The close anatomical relationship between the skeletal and connective systems of the pelvis, neurological, and vascular structures and pelvic organs are predisposing factors for structural and functional damages of the urogenital system. MATERIALS AND METHODS We performed PUBMED and MEDLINE search using terms "pelvic ring trauma/disruption, bladder injury, urethral injury, sexual...

Striated muscle associated with the female urethra and vagina constitute a continuous mass which appropriately may be called the urogenital sphincter. Though continuous, the muscle may be separated into two parts--one that surrounds the urethra, and the other surrounding the urethra and vagina. The individual muscle fibers are small and are embedded in connective tissue and infiltrated with smo...

Early delivery and low birth weight are strong predictors of the urogenital anomalies cryptorchidism (undescended testis) and hypospadias. Understanding these associations may lead to important etiologic clues. Therefore, the authors revisited the prevailing hypotheses regarding fetal growth restriction as a risk factor for urogenital anomalies. They studied a population of 934,538 Danish boys ...

Background: Congenital hypothyroidism (CH), as one of the most common congenital endocrine disorders, may be significantly associated with congenital malformations. This study investigates urogenital abnormalities in children with primary CH (PCH). Methods: This case-control study was conducted on 200 children aged three months to 1 year, referred to Amir-Kabir Hospital, Arak, Iran. One hundred...

The British Menopause Society Council aims to aid health professionals to inform and advise women about postreproductive health. This guidance refers to the long-term condition of urogenital atrophy. Treatment choice should be based on up to date information and targeted to individual women's needs. Non-estrogen and estrogen-based treatments are discussed.

In order to evaluate a possible role of several peptides in the human urogenital tract, peptide concentrations in urogenital tissues collected from surgery were measured using specific radioimmunoassay. The specimens were extracted in boiling 0.5M acetic acid, and these extracts were utilized to measure neuropeptide concentrations, i.e., neuropeptide Y(NPY), calcitonin gene-related peptide (CGR...

The Wilms tumor suppressor gene WT1 is essential for early urogenital development: homozygous mutations in WT1 result in embryonic lethality due to a failure in the development of kidneys and gonads. In the adult kidney, WT1 expression is limited to the glomerular podocytes. Several human nephrotic diseases arise from mutations of the WT1 gene, including mutations that affect its zinc-fingers a...

A 2-day ASPET/Ray Fuller symposium, entitled “Lower Urinary Tract Disorders: Physiology, Pharmacology and Therapeutic Approaches” sponsored by the American Society of Pharmacology and Experimental Therapeutics and organized by Michael G. Wyllie, Ph.D. (Urodoc Ltd., Herne Bay, Kent, UK) and James Sullivan, Ph.D. (Abbott Laboratories, Abbott Park, IL), was held at the Moscone Convention Center in...