Introduction. Neutrophil extracellular traps (NETs) and von Willebrand factor (vWF) are integral players in thrombosis inflammation cancer patients. It has been increasingly evident that an active interplay exists between NETs vWF. Some studies suggest cause decrease ADAMTS-13 (a disintegrin metalloprotease with thrombospondin type 1 motif, member 13) activity, being arm the pathogenesis of bot...

OBJECTIVE The objective of this study was to determine whether the presence of cervicitis influenced the accuracy of visual inspection with acetic acid (VIA). MATERIALS AND METHODS In a pilot study, 502 women from rural El Salvador were screened for cervical cancer using methods including colposcopy and VIA. The presence of cervicitis was assessed by grading the amount of inflammation on each...

A decrease in uterine cervical cancer (CC) mortality has been observed in developed countries. However, mortality data in Brazil suggest that CC is one of the most frequent causes of cancer death in women; it is the fourth cause of death from cancer in women in Rio Grande Sul State. A time-trend ecological study was performed to analyze CC mortality trends in Rio Grande do Sul from 1979 to 1998...

cervical cancer is the second most common malignant disease of women worldwide, and accounts for about one tenth of the total number of female cancer deaths. Even though uterine cervical cancer has been decreased as a result of widespread use of effective screening tests for premalig-nant lesions in developed countries, the cancer burden such as incidence and mortality is disproportionately hig...

This article describes the methodology of this bibliography. A search was conducted on the following: (1) bibliographic databases (PubMed, Scopus, and other databases) using search terms that maximize the retrieval of Malaysian publications; (2) Individual journal search of Malaysian healthrelated journals; (3) A targeted search of Google and Google Scholar; (4) Searching of Malaysian instituti...

Uterine cervical cancer is caused, mostly, by persistent infection with some types of Human Papilloma Virus (HPV), with types 16 and 18 showing higher risk for developing the disease. Because there is no effective drug treatment, early diagnosis of cervical cancer is very important for prognosis. The objective of this paper is to review the current immunohistochemical markers used in diagnosis,...

In a retrospective study of women who had undergone pelviscopic hysterectomies in the last 2 years, we focused on postoperative cyclic spotting. Preoperatively, a regular, cyclic menstruation and a premenopausal sexual hormone constellation were common to all patients. In the first group (n = 29), spotting occurred only in association with two uterine anatomical varieties: uterine hyperfiexion ...

sists mainly of collagen, hyaluronan, and proteoglycan. During gestation, it must close firmly to retain the fetus in the uterus. It undergoes ripening and dilatation at term, forming a parturient canal so that delivery can occur. During ripening, there are increases of collagen degradation in connective tissues, and proteoheparan sulfate, while decorin decreases. Inflammatory mediators, such a...

Cervical cancer is a serious disease that threatens the health of women worldwide. This study compared the sensitivities and false-positive rates of cervical cytology (Pap smear), human papilloma virus (HPV) DNA test, cervicography, first double-combined testing (cervical cytology and HPV DNA test), second double-combined testing (cervical cytology and cervicography) and triple-combined testing...