OBJECTIVE The aim of the study was to evaluate the safety and efficacy of vaginal estradiol (E2) softgel capsules for moderate-to-severe symptoms of vulvar and vaginal atrophy (VVA). Previous phase 1 studies showed lower systemic estrogen concentrations with this softgel capsule compared with an approved low-dose vaginal E2 tablet. METHODS In this randomized, double-blind, placebo-controlled ...

this is to report the case of a huge vaginal stone, and bladder calculi in a 26-year-old woman with previous operation of bladder exstrophy. it seems that the vaginal stone was secondary to the remaining wire used in her previous reconstructive surgery for pelvic closure 20 years ago and now surgery is performed to remove the vaginal and bladder stones.

STUDY OBJECTIVE The aim of this study was to estimate the cumulative incidence of vaginal cuff dehiscence in robotic-assisted total hysterectomies in our patients and to provide recommendations to decrease the incidence of vaginal cuff dehiscence. METHODS This was an observational case series, Canadian Task Force Classification II-3 conducted at an academic and community teaching hospital. A ...

OBJECTIVE This study aims to determine the emotional and physical impact of vaginal atrophy on North American postmenopausal women and their male partners. METHODS A weighted sample of 1,000 married or cohabiting North American postmenopausal women aged 55 to 65 years with vaginal discomfort and 1,000 male partners of postmenopausal women aged 55 to 65 years who experienced vaginal discomfort...

INTRODUCTION Wood's light lamp is a device that emits ultraviolet (UV) light and is a useful diagnostic tool for dermatologic disorders. The change in the thickness of vaginal mucosa, in vaginal atrophy, causes a change in its colour under Wood's light. We wanted to assess the feasibility of Wood's light (WL) as a diagnostic tool for vaginal atrophy. MATERIALS AND METHODS The study was conduc...

vaginal leiomyomas are uncommon benign tumour with variable clinical presentation. these tumours arise most commonly from anterior vaginal wall. we report a case of 50-year old postmenopausal woman who presented with urinary retention, profuse vaginal bleeding and mass protruding into vagina. local examination revealed a pedunculated mass attached to the posterior vaginal wall with vascular sta...

The estrogenic efficacy of topical vaginal application of Pueraria mirifica extract (PM) on the restoration of vaginal atrophy, and the presence of any systemic side effects, were investigated in postmenopausal cynomolgus macaques. Twelve postmenopausal cynomolgus macaques, with complete cessation of menstruation for at least 5 years before start of this experiment, were divided into three grou...

OBJECTIVE The purpose of this study was to compare the cost-effectiveness of laparoscopic-assisted vaginal hysterectomy to traditional total abdominal hysterectomy and total vaginal hysterectomy with regard not only to direct hospital costs but also to indirect costs. STUDY DESIGN This was a combined retrospective cohort study (Canadian Task Force classification II-2) that was conducted in a ...

Leiomyoma in the female genital tract is a common benign tumor of the uterus, followed by cervix, round ligament and inguinal ligament. Vaginal leiomyoma is a rare entity with only about 300 reported cases. Here, we report a case of a vaginal leiomyoma in a 22 year old nullipara who presented with dyspareunia and infertility. Vaginal examination revealed a mass in the anterior vaginal wall. MRI...