Azidothymidine (AZT or ZVD), a Nucleoside Reverse Transcriptase Inhibitor (NRTI), is used as antiviral medication to treat Human Immunodeficiency Virus (HIV) which causes Acquired Immunodeficiency Syndrome (AIDS). It is the first approved anti HIV drug for AIDS used either in combination with other antiretroviral agents or as a single drug and is also included in WHO’s national list of essentia...

The present review sheds some light on family planning methods and contraceptive dosage forms in use nowadays and new ones under investigation. First, the benefits of family planning for women, men, children, nation and the world are addressed. Then a complete survey about the methods of contraception in use nowadays viz: pills, IUD, vaginal rings, injectables, barriers, natural methods, spermi...

Pelletization process first came into existence way back during the 1950s, when the first product was introduced to the market. These pelletized dosage forms have gained popularity considerably from then because of their distinct advantages, such as ease of capsule filling because of better flow properties of the perfectly spherical pellets; enhancement of drug dissolution; ease of coating; sus...

OBJECTIVE Local estrogens are used for the treatment of genitourinary symptoms of menopause. The efficacy and adverse effects of both estrogen-containing vaginal tablets (VT) and estrogen-containing vaginal creams (VC)/gels are comparable. Our objective was to assess the compliance and adherence to treatment in a large population. METHODS A retrospective study on women aged 40 to 89 was perfo...

combination dosage forms of naproxen sodium and pseudoephedrine hydrochloride are used for symptomatic treatment of cold and sinus disorders. in this study, fourth-order derivative spectrophotometric method was used for simultaneous determination of naproxen sodium and pseudoephedrine hydrochloride. the method was linear over the range of 2-28 μg/ml for pseudoephedrine hydrochloride and 4-200 μ...

INTRODUCTION Pharmaceutical industry is no longer allowed to develop new medicines for use in adults only, as the 2007 Paediatric Regulation requires children to be considered also. The plans for such paediatric development called Paediatric Investigation Plans (PIPs) are subject to agreement by the European Medicines Agency (EMA) and its Paediatric Committee (PDCO). The aim of this study was t...

OBJECTIVE To perform a pilot project to determine if this research design was appropriate to explore potential causal relationships between oral probiotic use and vaginal Group B Streptococcal (GBS) colonisation rates in pregnant women. METHOD Thirty-four GBS-positive women at 36 weeks pregnant were recruited. The participants were randomly allocated to the control group, who received standar...