Endothelial cells are critical mediators of haemodynamic forces and as such are important foci for initiation of vascular pathology. Valvular leaflets are also lined with endothelial cells, though a similar role in mechanosensing has not been demonstrated. Recent evidence has shown that valvular endothelial cells respond morphologically to shear stress, and several studies have implicated valvu...

OBJECTIVE To report the prevalence of esophagitis in patients with pH-documented laryngopharyngeal reflux. STUDY DESIGN Prospective study of 58 consecutive patients with documented laryngopharyngeal reflux, all of whom underwent transnasal esophagoscopy as part of their reflux evaluations. METHODS All patients with a diagnosis of laryngopharyngeal reflux confirmed by abnormal pharyngeal pH ...

HYPOTHESIS Symptom control does not reflect elimination of abnormal acid reflux or abnormal bile reflux in patients with long-segment Barrett esophagus receiving proton pump inhibitors (PPIs). DESIGN Prospective survey. SETTING University hospital. PATIENTS Thirty-two patients with long-segment Barrett esophagus who were asymptomatic with PPIs. MAIN OUTCOME MEASURES Twenty-four-hour amb...

background: reflux disease is a common gastrointestinal problem. the association between reflux disease and gastritis pattern is controversial. aim : to determine the association between reflux disease and gastritis pattern in patients with helicobacter pylori (h. pylori) infection. methods: 470 patients with dyspepsia and reflux disease were enrolled in this study. the inclusion criteria were ...

Classic anti reflux procedures on children with a history of posterior urethral valve does not usually yield good results and often ends up with ureteral obstruction and even permanent urinary diversion. From 1981 through 1988,21 boys with history of posterior urethral valve (PUV) underwent evaluation for vesicoureteral (VU) reflux 17 boys had VU reflux. Following valve ablation, reflux di...

BACKGROUND Data on the prevalence of valvular heart disease in very old individuals are scarce and based mostly on in-hospital series. In addition, the potential detrimental effect of valvular heart disease on the activities of daily living is unknown. The present study evaluated the prevalence of significant valvular heart disease and the impact of valvular heart disease on the activities of d...

We examined the relationship between microscopic hematuria and inferior vena cava (IVC) reflux. Transabdominal color Doppler ultrasonography of the IVC was performed in the supine position with the convex probe positioned perpendicular to the upper abdominal wall, and the extent of reflux into the IVC with each heart beat was examined near the diaphragm. A total of 171 patients were studied who...