Objectives This study assessed the effectiveness and patient experience of the ClariVein® endovenous occlusion catheter for varicose veins from a large single-centre series in the UK. Methods A total of 300 patients (371 legs) underwent ClariVein® treatment for their varicose veins; 184 for great saphenous vein (GSV) incompetence, 62 bilateral GSV, 23 short saphenous vein (SSV), 6 bilateral SSV...

QUESTIONS UNDER STUDY To determine the efficacy of compression stockings in preventing emergent varicose veins in pregnancy. METHODS A prospective randomised controlled study in the outpatient department of the University Hospital of Zurich, Switzerland, including women with uncomplicated pregnancies <12 weeks at outset of study. A no-stockings control group (n = 15) was compared with two tre...

Chronic venous disease encompasses a broad range of conditions from minor telangiectasia to varicose veins to severe venous insufficiency with venous ulcers. The common underlying mechanism for chronic venous disease is congestion and stasis caused by reversal of venous flow and valve failure. Patients with primary varicose veins have venous congestion limited to the superficial venous system, ...

OBJECTIVE The objective of this study was to report a phenomenon in patients with primary varicose veins that resembles neovascular tissue in postsurgical recurrences-primary avalvular varicose anomalies (PAVA). METHODS Between March 2012 and July 2013, 756 patients (122 men, 634 women) with primary varicose veins (mean age, 53 years; range, 18-89 years) underwent duplex ultrasonography with ...

BACKGROUND Despite the high prevalence of chronic venous insufficiency and varicose veins in the Western world, suitable pharmaceutical therapies for these venous diseases have not been explored to date. In this context, we recently reported that a chronic increase in venous wall stress or biomechanical stretch is sufficient to cause development of varicose veins through the activation of the t...

The effect of maintaining pulmonary nitrogenation on venous admixture during halothane anaesthesia and on postoperative hypoxaemia was studied in patients undergoing either abdominal surgery or the removal of varicose veins. In both groups venous admixture was greater when nitrogen replaced nitrous oxide in the anaesthetic gas mixture. In the varicose vein group hypoxaemia was more severe in th...

BACKGROUND Endovenous Laser Ablation (EVLA) is one of the most accepted treatment options for varicose veins. The aim of this study was to investigate the efficacy and safety of the new radial fiber slim (ELVeS-radial-slim kit™) for the 1470 nm diode laser in perforator veins with a 1 month follow-up. METHODS Our prospective observational cohort study comprised 69 perforating veins in 55 pati...

Aim: To comparative analysis of vein stripping versus no in varicose disease. Study design: Comparative study Place and duration study: Department Surgery, CMH Kharian Medical College, from 01-01-2019 to 31-12-2021. Methodology: Eighty cases which were having sapheno-femoral valve incompetence as well perforators-incompetence enrolled. The age the was between 16 70 year. Electrocardiography (EC...

To explore the cellular adaptations and responses to hypoxia in normal human saphenous vein smooth muscle cells (SMCs) and presume what roles phenotypic modulation of normal human saphenous vein SMCs would play in varicose vein of lower extremity, we used cobalt chloride (CoCl2), a hypoxia mimetic, to treat normal human saphenous vein SMCs in vitro. The proliferating ability of cells exposed to...