نتایج جستجو برای: vascular tumor
تعداد نتایج: 628077 فیلتر نتایج به سال:
UNLABELLED Dissemination of tumor cells is an essential step in metastasis. Direct contact between a macrophage, mammalian-enabled (MENA)-overexpressing tumor cell, and endothelial cell [Tumor MicroEnvironment of Metastasis (TMEM)] correlates with metastasis in breast cancer patients. Here we show, using intravital high-resolution two-photon microscopy, that transient vascular permeability and ...
Successful treatment of solid tumors with chemotherapeutics requires that adequate levels reach the tumor cells. Tumor vascular normalization has been proposed to enhance drug delivery and improve tumor response to chemotherapy. Differently, augmenting leakage of the tumor-associated vasculature, and as such enhance vascular abnormality, may improve tumor response as well. In the present study,...
BACKGROUND Vascular endothelial growth factor (VEGF) receptor-2 is the major mediator of the mitogenic, angiogenic, and vascular hyperpermeability effects of VEGF on breast tumors. Overexpression of VEGF and VEGF receptor-2 is associated with the degree of pathomorphosis of the tumor tissue and unfavorable prognosis. In this study, we demonstrate that non-invasive quantification of the degree o...
isolated third nerve palsy develops in numerous intracranial pathologies such as closed head trauma, tumor, and aneurysm. this report describes a 61 years old female with an abrasion on the left forehead and ptosis of the left eye. initial computed tomography did not reveal any causative cerebral and vascular lesions or orbital and cranial fractures. high-resolution and multi-axial enhanced mag...
Background: Glomus jugulare tumors are encapsulated, slowly growing, highly vascular and locally invasive tumors. These tumors arise from para-ganglionic cells and they are histologically benign. The purpose of this study is to evaluate Gamma Knife Radiosurgery (GKRS) on the local tumor control.Methods: This study is an observational cross-sectional research in which thirty-four patients wi...
Successful treatment of solid tumors with chemotherapeutics requires that adequate levels reach the tumor cells. Tumor vascular normalization has been proposed to enhance drug delivery and improve tumor response to chemotherapy. Differently, augmenting leakage of the tumor-associated vasculature, and as such enhance vascular abnormality, may improve tumor response as well. In the present study,...
Among the renal lesions described, cell carcinoma (RCC) is primary neoplastic tumor reaching males in a proportion two times higher than females and characterizing about 2% of carcinomas adult population. Although treatment this type cancer has evolved recent years, management patients with metastatic conditions remains challenging, possible spreads to lungs bones. Vascular metastasis RCC skin,...
Over the past several decades, a tube formation assay using growth factor-reduced Matrigel has been typically employed to demonstrate the angiogenic activity of vascular endothelial cells in vitro. However, recently growing evidence has shown that this assay is not limited to test vascular behavior for endothelial cells. Instead, it also has been used to test the ability of a number of tumor ce...
background and purpose: cancer and cerebrovascular accidents (cva) are two most common causes of mortality and morbidity in the elderly. patients with brain tumor can be highly affected by postsurgical stroke. cva may be the first manifestation in these patients . therefore, we aimed to assess the epidemiological factors affecting cva after brain surgery. methods: in this cross-sectional study ...
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